| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 248 | 34 | 47 | 0.329 | 0.375 | 3.01 | 1B |
| Dustin Pedroia | 246 | 29 | 18 | 0.240 | 0.350 | -0.51 | 2B |
| Jacoby Ellsbury | 239 | 36 | 27 | 0.292 | 0.360 | 1.32 | CF |
| David Ortiz | 221 | 31 | 27 | 0.310 | 0.380 | 1.19 | DH |
| Carl Crawford | 221 | 25 | 21 | 0.233 | 0.267 | -0.07 | LF |
| Kevin Youkilis | 216 | 32 | 34 | 0.260 | 0.384 | 2.15 | 3B |
| Jed Lowrie | 178 | 24 | 21 | 0.306 | 0.354 | 0.78 | SS-3B |
| J.D. Drew | 161 | 12 | 10 | 0.228 | 0.342 | -1.26 | RF |
| Jarrod Saltalamacchia | 119 | 12 | 15 | 0.218 | 0.277 | 0.20 | CR |
| Jason Varitek | 91 | 8 | 8 | 0.235 | 0.308 | -0.34 | CR |
| Marco Scutaro | 76 | 4 | 8 | 0.235 | 0.316 | -0.42 | SS |
| Mike Cameron | 67 | 7 | 7 | 0.190 | 0.254 | -0.01 | CF |
| Drew Sutton | 27 | 5 | 5 | 0.269 | 0.259 | 0.45 | X |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.30 | RF-LF-CF |
| Josh Reddick | 11 | 3 | 4 | 0.556 | 0.545 | 0.49 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 75.3 | 3.94 | 12 | 0 | X | -0.10 |
| Josh Beckett | 70.0 | 1.80 | 11 | 0 | X | 3.41 |
| Clay Buchholz | 66.0 | 3.41 | 11 | 0 | X | 0.74 |
| John Lackey | 39.3 | 8.01 | 7 | 0 | X | -3.78 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.23 |
| Tim Wakefield | 37.0 | 4.14 | 4 | 9 | X | -0.21 |
| Alfredo Aceves | 33.3 | 3.51 | 3 | 11 | X | 0.29 |
| Daniel Bard | 25.7 | 3.51 | 0 | 25 | X | 0.23 |
| Jonathan Papelbon | 22.7 | 2.78 | 0 | 22 | X | 0.59 |
| Matt Albers | 20.3 | 3.54 | 0 | 15 | X | 0.16 |
| Dan Wheeler | 15.0 | 8.40 | 0 | 15 | X | -1.58 |
| Scott Atchison | 12.3 | 5.11 | 0 | 6 | X | -0.35 |
| Bobby Jenks | 9.7 | 8.38 | 0 | 12 | X | -1.01 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 8 | X | 0.73 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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