| Starter | Tm | Tier | Game |
|---|---|---|---|
| Red Faber | CHA | 11.04 | 192109300_CLE_CHA |
| Eppa Rixey | CIN | 5.27 | 192110021_CHN_CIN |
| Burleigh Grimes | LAN | 4.65 | 192110020_SFN_LAN |
| Carl Mays | NYA | 4.2 | 192110011_OAK_NYA |
| George Mogridge | MIN | 3.14 | 192109300_MIN_BOS |
| Starter | Tm | Tier | Game |
|---|---|---|---|
| Roy Wilkinson | CHA | -3.02 | 192110020_CLE_CHA |
| Dixie Davis | BAL | -1.44 | 192110020_BAL_DET |
| Virgil Cheeves | CHN | -1.28 | 192110022_CHN_CIN |
| Jimmy Ring | PHI | -0.98 | 192110012_SFN_PHI |
| Curt Fullerton | BOS | -0.48 | 192110020_BOS_NYA |
Based on accumulated WAA for this season up to 1921-10-02.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +002+ | 12.38 | Red Faber | 330.7 | CHA |
| +009+ | 9 | Eppa Rixey | 300.7 | CIN |
| +011+ | 8.49 | Burleigh Grimes | 302.3 | LAN |
| +012+ | 7.88 | Carl Mays | 336 | NYA |
| +013+ | 7.06 | Bill Doak | 208.7 | SLN |
| +015+ | 6.78 | George Mogridge | 288.7 | MIN |
| +018+ | 6.4 | Waite Hoyt | 282.7 | NYA |
| +019+ | 6.24 | Whitey Glazner | 234 | PIT |
| +021+ | 5.94 | Sad Sam Jones | 298.7 | BOS |
| +022+ | 5.66 | Jesse Barnes | 258.7 | SFN |
| +026+ | 5.06 | Clarence Mitchell | 190 | LAN |
| +025+ | 5.06 | Wilbur Cooper | 327 | PIT |
| +027+ | 4.94 | Stan Coveleski | 315.3 | CLE |
| +028+ | 4.91 | Dolf Luque | 304 | CIN |
| +036+ | 4.11 | Rube Marquard | 264.7 | CIN |
| +039+ | 3.86 | Pete Alexander | 251.3 | CHN |
| +040+ | 3.71 | Urban Shocker | 326.7 | BAL |
| +042+ | 3.48 | Johnny Morrison | 144 | PIT |
| +044+ | 3.28 | Joe Oeschger | 299 | ATL |
| +045+ | 3.25 | Bill Pertica | 208.3 | SLN |
| +047+ | 3.1 | Bullet Joe Bush | 253.3 | BOS |
| +048+ | 3.08 | Jesse Haines | 244.3 | SLN |
| +051+ | 3 | Walter Johnson | 264 | MIN |
| +052+ | 3 | Dana Fillingim | 239.7 | ATL |
| +054+ | 2.89 | Bill Sherdel | 144.3 | SLN |
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