| Starter | Tm | Tier | Game |
|---|---|---|---|
| Eppa Rixey | CIN | 5.29 | 192107240_CHN_CIN |
| Jesse Barnes | SFN | 4.77 | 192107232_CIN_SFN |
| Pete Alexander | CHN | 3.45 | 192107230_CHN_PHI |
| Babe Adams | PIT | 2.15 | 192107250_SFN_PIT |
| George Mogridge | MIN | 1.39 | 192107230_MIN_DET |
| Starter | Tm | Tier | Game |
|---|---|---|---|
| Shovel Hodge | CHA | -6.71 | 192107240_OAK_CHA |
| Dixie Davis | BAL | -1.82 | 192107230_BOS_BAL |
| Howard Ehmke | DET | -1.36 | 192107230_MIN_DET |
| Bob Hasty | OAK | -1.28 | 192107230_OAK_CHA |
| Bill Hubbell | PHI | -0.69 | 192107240_PHI_SFN |
Based on accumulated WAA for this season up to 1921-07-25.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +002+ | 9.56 | Red Faber | 223.7 | CHA |
| +003+ | 8.65 | Eppa Rixey | 180 | CIN |
| +008+ | 5.56 | Carl Mays | 194.7 | NYA |
| +009+ | 5.46 | George Mogridge | 176.7 | MIN |
| +012+ | 5.12 | Jesse Barnes | 148.7 | SFN |
| +016+ | 4.37 | Pete Alexander | 131 | CHN |
| +018+ | 3.88 | Sad Sam Jones | 184 | BOS |
| +019+ | 3.77 | Bill Doak | 114.7 | SLN |
| +020+ | 3.76 | Whitey Glazner | 144 | PIT |
| +021+ | 3.74 | Burleigh Grimes | 157 | LAN |
| +024+ | 3.57 | Wilbur Cooper | 190 | PIT |
| +026+ | 3.48 | Hugh McQuillan | 166 | ATL |
| +028+ | 3.28 | Babe Adams | 111.3 | PIT |
| +030+ | 3.06 | Dolf Luque | 178.7 | CIN |
| +031+ | 2.85 | Elmer Ponder | 57.7 | TOT |
| +032+ | 2.68 | Dana Fillingim | 139.3 | ATL |
| +034+ | 2.6 | Bob Shawkey | 136.7 | NYA |
| +035+ | 2.55 | Herb Pennock | 131 | BOS |
| +038+ | 2.46 | Waite Hoyt | 159.7 | NYA |
| +039+ | 2.31 | Bullet Joe Bush | 130.7 | BOS |
| +042+ | 2.24 | Joe Oeschger | 173 | ATL |
| +049+ | 2.05 | Stan Coveleski | 195.7 | CLE |
| +051+ | 2.02 | Earl Hamilton | 145.7 | PIT |
| +052+ | 1.97 | Fred Toney | 137.7 | SFN |
| +058+ | 1.81 | Rosy Ryan | 111.7 | SFN |
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