| Starter | Tm | Tier | Game |
|---|---|---|---|
| Red Faber | CHA | 5.98 | 192107170_BOS_CHA |
| Jesse Barnes | SFN | 4.99 | 192107170_PIT_SFN |
| Eppa Rixey | CIN | 3.8 | 192107161_CIN_PHI |
| Wilbur Cooper | PIT | 3.22 | 192107160_PIT_SFN |
| Pete Alexander | CHN | 2.99 | 192107161_CHN_LAN |
| Starter | Tm | Tier | Game |
|---|---|---|---|
| Roy Wilkinson | CHA | -3.28 | 192107160_BOS_CHA |
| Ray Caldwell | CLE | -1.9 | 192107170_MIN_CLE |
| Harry Courtney | MIN | -1.32 | 192107160_MIN_CLE |
| Bill Hubbell | PHI | -1.2 | 192107162_CIN_PHI |
| Bob Hasty | OAK | -0.96 | 192107150_OAK_DET |
Based on accumulated WAA for this season up to 1921-07-17.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +002+ | 8.74 | Red Faber | 209.7 | CHA |
| +005+ | 7.33 | Eppa Rixey | 162 | CIN |
| +007+ | 5.99 | Carl Mays | 181 | NYA |
| +009+ | 5.23 | George Mogridge | 160.7 | MIN |
| +013+ | 4.63 | Jesse Barnes | 143.7 | SFN |
| +019+ | 3.53 | Burleigh Grimes | 144 | LAN |
| +021+ | 3.47 | Sad Sam Jones | 165.3 | BOS |
| +023+ | 3.28 | Herb Pennock | 126.7 | BOS |
| +024+ | 3.24 | Bill Doak | 104.3 | SLN |
| +027+ | 2.95 | Stan Coveleski | 188.7 | CLE |
| +028+ | 2.73 | Hugh McQuillan | 154 | ATL |
| +029+ | 2.7 | Dana Fillingim | 118 | ATL |
| +030+ | 2.59 | Pete Alexander | 111 | CHN |
| +031+ | 2.57 | Waite Hoyt | 142.7 | NYA |
| +032+ | 2.49 | Dolf Luque | 168.3 | CIN |
| +034+ | 2.42 | Wilbur Cooper | 172 | PIT |
| +035+ | 2.36 | Joe Oeschger | 159 | ATL |
| +036+ | 2.34 | Allen Russell | 112.7 | BOS |
| +037+ | 2.34 | Rosy Ryan | 99.7 | SFN |
| +046+ | 2.1 | Babe Adams | 93.3 | PIT |
| +055+ | 1.75 | Bob Shawkey | 120.7 | NYA |
| +056+ | 1.74 | Fred Toney | 128.7 | SFN |
| +058+ | 1.72 | Johnny Morrison | 46 | PIT |
| +059+ | 1.71 | Bullet Joe Bush | 112.7 | BOS |
| +062+ | 1.65 | Earl Hamilton | 136.3 | PIT |
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