| Starter | Tm | Tier | Game |
|---|---|---|---|
| Pete Alexander | CHN | 3.85 | 192106260_PIT_CHN |
| Stan Coveleski | CLE | 3.62 | 192106280_BAL_CLE |
| Babe Adams | PIT | 3.13 | 192106260_PIT_CHN |
| Burleigh Grimes | LAN | 2.62 | 192106270_ATL_LAN |
| Eppa Rixey | CIN | 1.26 | 192106270_CIN_SLN |
| Starter | Tm | Tier | Game |
|---|---|---|---|
| Speed Martin | CHN | -1.18 | 192106281_PIT_CHN |
| Waite Hoyt | NYA | -0.92 | 192106260_MIN_NYA |
| Bill Hubbell | PHI | -0.64 | 192106270_SFN_PHI |
| Emilio Palmero | BAL | -0.59 | 192106260_BAL_CLE |
| Elmer Myers | BOS | -0.48 | 192106280_OAK_BOS |
Based on accumulated WAA for this season up to 1921-06-28.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +004+ | 5.81 | Carl Mays | 143.7 | NYA |
| +006+ | 5.41 | Red Faber | 154.3 | CHA |
| +007+ | 5.35 | Eppa Rixey | 129.3 | CIN |
| +009+ | 4.37 | Burleigh Grimes | 106 | LAN |
| +010+ | 4.19 | George Mogridge | 120 | MIN |
| +015+ | 3.42 | Herb Pennock | 101.7 | BOS |
| +018+ | 3.26 | Wilbur Cooper | 133 | PIT |
| +020+ | 3.2 | Whitey Glazner | 110 | PIT |
| +023+ | 3.06 | Stan Coveleski | 153.3 | CLE |
| +024+ | 3.06 | Earl Hamilton | 119.7 | PIT |
| +025+ | 2.92 | Dana Fillingim | 98.3 | ATL |
| +026+ | 2.83 | Dolf Luque | 133.7 | CIN |
| +027+ | 2.81 | Bill Piercy | 63.3 | NYA |
| +028+ | 2.52 | Fred Toney | 107.7 | SFN |
| +039+ | 1.98 | Rube Benton | 63.3 | SFN |
| +040+ | 1.97 | Rube Marquard | 120.7 | CIN |
| +041+ | 1.95 | Bill Doak | 78.3 | SLN |
| +043+ | 1.81 | Red Causey | 49.7 | PHI |
| +051+ | 1.63 | Allen Russell | 81.7 | BOS |
| +060+ | 1.5 | Bullet Joe Bush | 74 | BOS |
| +063+ | 1.43 | Dave Keefe | 94.7 | OAK |
| +064+ | 1.41 | Hugh McQuillan | 122 | ATL |
| +065+ | 1.39 | Babe Adams | 77.3 | PIT |
| +067+ | 1.32 | Elam Vangilder | 45.3 | BAL |
| +068+ | 1.32 | Roy Walker | 74 | SLN |
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