| Tm | Name | W | L | Start | End | |
|---|---|---|---|---|---|---|
| BOS | Ed Barrow | 75 | 51 | Beg | End | |
| BOS | George Stallings | 53 | 71 | Beg | End | |
| CHA | Pants Rowland | 57 | 67 | Beg | End | |
| CHN | Fred Mitchell | 84 | 45 | Beg | End | |
| CIN | Christy Mathewson | 61 | 57 | Beg | 19180825 | |
| CIN | Heinie Groh | 7 | 3 | 19180828 | End | |
| CLE | Lee Fohl | 73 | 54 | Beg | End | |
| DET | Hughie Jennings | 55 | 71 | Beg | End | |
| LAN | Wilbert Robinson | 57 | 69 | Beg | End | |
| NYA | Miller Huggins | 60 | 63 | Beg | End | |
| OAK | Connie Mack | 52 | 76 | Beg | End | |
| PHI | Pat Moran | 55 | 68 | Beg | End | |
| PIT | Hugo Bezdek | 65 | 60 | Beg | End | |
| SFN | John McGraw | 71 | 53 | Beg | End | |
| SLN | Jack Hendricks | 51 | 78 | Beg | End | |
| SLN | Fielder Jones | 22 | 24 | Beg | 19180612 | |
| SLN | Jimmy Austin | 7 | 9 | 19180613 | 19180626 | |
| SLN | Jimmy Burke | 29 | 31 | 19180628 | End | |
| TEX | Clark Griffith | 72 | 56 | Beg | End |
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