| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 649 | 89 | 97 | 0.204 | 0.333 | 4.25 | DH-1B |
| Alex Rios | 640 | 93 | 93 | 0.304 | 0.334 | 4.46 | RF |
| Alexei Ramirez | 621 | 59 | 72 | 0.265 | 0.285 | -0.87 | SS |
| Paul Konerko | 598 | 74 | 75 | 0.298 | 0.371 | 1.57 | 1B-DH |
| Alejandro de Aza | 585 | 80 | 50 | 0.281 | 0.347 | -0.12 | CF-LF |
| Gordon Beckham | 583 | 62 | 60 | 0.233 | 0.292 | -0.92 | 2B |
| Dayan Viciedo | 543 | 67 | 78 | 0.255 | 0.300 | 2.44 | LF-DH |
| A.J. Pierzynski | 520 | 70 | 77 | 0.278 | 0.325 | 3.19 | CR |
| Kevin Youkilis | 344 | 47 | 46 | 0.236 | 0.346 | 1.67 | 3B-1B |
| Dewayne Wise | 176 | 20 | 24 | 0.258 | 0.295 | 0.48 | LF |
| Tyler Flowers | 153 | 19 | 13 | 0.213 | 0.294 | -0.24 | CR |
| Orlando Hudson | 151 | 10 | 17 | 0.199 | 0.258 | -0.72 | 2B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.95 | 3B |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.81 | X |
| Jordan Danks | 75 | 7 | 4 | 0.224 | 0.280 | -0.61 | LF-CF |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.81 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.57 | LF |
| Ray Olmedo | 42 | 6 | 1 | 0.244 | 0.238 | -0.25 | 3B |
| Dan Johnson | 31 | 10 | 6 | 0.364 | 0.548 | 0.95 | X |
| Jose Lopez | 24 | 0 | 0 | 0.217 | 0.250 | -0.57 | 3B-DH-1B |
| Hector Gimenez | 11 | 1 | 1 | 0.455 | 0.455 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 219.0 | 3.37 | 32 | 0 | X | 3.25 |
| Chris Sale | 192.0 | 3.05 | 29 | 1 | X | 4.29 |
| Gavin Floyd | 168.0 | 4.29 | 29 | 0 | X | -1.10 |
| Jose Quintana | 136.3 | 3.76 | 22 | 3 | X | 0.77 |
| Philip Humber | 102.0 | 6.44 | 16 | 10 | X | -5.80 |
| Nate Jones | 71.7 | 2.39 | 0 | 65 | X | 2.71 |
| Hector Santiago | 70.3 | 3.33 | 4 | 38 | X | 1.11 |
| Matt Thornton | 65.0 | 3.46 | 0 | 74 | X | 0.82 |
| Francisco Liriano | 56.7 | 5.40 | 11 | 1 | X | -1.84 |
| Addison Reed | 55.0 | 4.58 | 0 | 62 | X | -0.74 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.12 |
| Dylan Axelrod | 51.0 | 5.47 | 7 | 7 | X | -1.74 |
| Jesse Crain | 48.0 | 2.25 | 0 | 51 | X | 1.97 |
| Brett Myers | 34.7 | 3.12 | 0 | 35 | X | 0.72 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.40 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.50 |
| Brian Omogrosso | 21.0 | 2.57 | 0 | 17 | X | 0.70 |
| Leyson Septimo | 14.3 | 5.02 | 0 | 21 | X | -0.34 |
| Donnie Veal | 13.0 | 2.08 | 0 | 24 | X | 0.58 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Jhan Marinez | 2.7 | 0.00 | 0 | 2 | X | 0.25 |
| Deunte Heath | 2.0 | 4.50 | 0 | 3 | X | -0.02 |
| Dewayne Wise | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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