| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 620 | 82 | 65 | 0.289 | 0.345 | 0.96 | 2B |
| Mike Aviles | 546 | 56 | 61 | 0.250 | 0.280 | -0.46 | SS |
| Adrian Gonzalez | 527 | 65 | 86 | 0.300 | 0.343 | 3.55 | 1B |
| Cody Ross | 525 | 70 | 82 | 0.264 | 0.324 | 3.70 | RF-LF-DH |
| Jarrod Saltalamacchia | 444 | 55 | 59 | 0.224 | 0.291 | 1.61 | CR-DH |
| David Ortiz | 383 | 68 | 60 | 0.318 | 0.415 | 4.50 | DH |
| Jacoby Ellsbury | 319 | 42 | 26 | 0.271 | 0.313 | -0.31 | CF |
| Daniel Nava | 313 | 38 | 33 | 0.243 | 0.351 | 0.15 | LF |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.56 | 3B |
| Pedro Ciriaco | 269 | 31 | 20 | 0.288 | 0.305 | -0.92 | 3B-2B-SS-DH |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.12 | RF-CF |
| Scott Podsednik | 215 | 19 | 14 | 0.302 | 0.312 | -1.55 | LF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.24 | 3B-1B |
| Ryan Lavarnway | 162 | 11 | 12 | 0.160 | 0.210 | -1.37 | CR-DH |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.22 | CR |
| Nick Punto | 148 | 13 | 10 | 0.200 | 0.297 | -1.04 | 2B |
| Carl Crawford | 125 | 23 | 19 | 0.280 | 0.304 | 1.49 | LF |
| Mauro Gomez | 111 | 15 | 17 | 0.275 | 0.324 | 0.77 | 1B |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Ryan Kalish | 103 | 12 | 6 | 0.229 | 0.272 | -0.51 | CF |
| James Loney | 102 | 5 | 8 | 0.240 | 0.275 | -1.02 | 1B |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Jose Iglesias | 74 | 5 | 1 | 0.108 | 0.189 | -1.10 | SS |
| Danny Valencia | 28 | 1 | 5 | 0.148 | 0.143 | -0.02 | 3B |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Che-Hsuan Lin | 12 | 1 | 0 | 0.250 | 0.250 | -0.18 | X |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Ivan De Jesus | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Guillermo Quiroz | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 205.3 | 4.78 | 33 | 0 | X | -3.65 |
| Clay Buchholz | 189.3 | 4.56 | 29 | 0 | X | -2.42 |
| Felix Doubront | 161.0 | 4.86 | 29 | 0 | X | -3.19 |
| Josh Beckett | 127.3 | 5.23 | 21 | 0 | X | -3.61 |
| Aaron Cook | 94.0 | 5.65 | 18 | 0 | X | -3.58 |
| Alfredo Aceves | 84.0 | 5.36 | 0 | 69 | X | -2.63 |
| Franklin Morales | 76.3 | 3.66 | 9 | 28 | X | 0.64 |
| Daniel Bard | 59.3 | 6.22 | 10 | 7 | X | -3.05 |
| Scott Atchison | 50.7 | 1.78 | 0 | 41 | X | 2.65 |
| Vicente Padilla | 50.0 | 4.50 | 0 | 56 | X | -0.57 |
| Mark Melancon | 45.0 | 6.20 | 0 | 41 | X | -2.29 |
| Daisuke Matsuzaka | 43.3 | 7.68 | 10 | 0 | X | -3.71 |
| Junichi Tazawa | 43.0 | 1.47 | 0 | 36 | X | 2.56 |
| Andrew Miller | 40.3 | 3.35 | 0 | 53 | X | 0.63 |
| Clayton Mortensen | 40.0 | 2.48 | 0 | 25 | X | 1.44 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.58 |
| Rich Hill | 19.7 | 1.83 | 0 | 25 | X | 1.00 |
| Craig Breslow | 19.3 | 2.79 | 0 | 22 | X | 0.55 |
| Andrew Bailey | 15.3 | 7.04 | 0 | 19 | X | -1.08 |
| Pedro Beato | 6.7 | 2.70 | 0 | 3 | X | 0.20 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Zach Stewart | 5.7 | 22.24 | 2 | 0 | X | -2.41 |
| Chris Carpenter | 5.7 | 1.59 | 0 | 7 | X | 0.32 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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