| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 614 | 81 | 64 | 0.288 | 0.344 | 0.84 | 2B |
| Mike Aviles | 546 | 56 | 61 | 0.250 | 0.280 | -0.51 | SS |
| Adrian Gonzalez | 527 | 65 | 86 | 0.300 | 0.343 | 3.51 | 1B |
| Cody Ross | 520 | 70 | 81 | 0.266 | 0.327 | 3.67 | RF-LF-DH |
| Jarrod Saltalamacchia | 439 | 55 | 59 | 0.224 | 0.289 | 1.68 | CR-DH |
| David Ortiz | 383 | 68 | 60 | 0.318 | 0.415 | 4.47 | DH |
| Jacoby Ellsbury | 313 | 41 | 26 | 0.273 | 0.316 | -0.30 | CF |
| Daniel Nava | 307 | 38 | 33 | 0.247 | 0.352 | 0.26 | LF |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.54 | 3B |
| Pedro Ciriaco | 264 | 31 | 20 | 0.285 | 0.299 | -0.83 | 3B-2B-SS-DH |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.14 | RF-CF |
| Scott Podsednik | 215 | 19 | 14 | 0.302 | 0.312 | -1.57 | LF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.23 | 3B-1B |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.24 | CR |
| Ryan Lavarnway | 157 | 11 | 12 | 0.166 | 0.217 | -1.26 | CR-DH |
| Nick Punto | 148 | 13 | 10 | 0.200 | 0.297 | -1.05 | 2B |
| Carl Crawford | 125 | 23 | 19 | 0.280 | 0.304 | 1.48 | LF |
| Mauro Gomez | 111 | 15 | 17 | 0.275 | 0.324 | 0.76 | 1B |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.80 | CF |
| Ryan Kalish | 103 | 12 | 6 | 0.229 | 0.272 | -0.52 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | -0.01 | X |
| James Loney | 97 | 4 | 7 | 0.231 | 0.268 | -1.12 | 1B |
| Jose Iglesias | 69 | 5 | 1 | 0.117 | 0.203 | -0.99 | SS |
| Danny Valencia | 28 | 1 | 5 | 0.148 | 0.143 | -0.03 | 3B |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Che-Hsuan Lin | 12 | 1 | 0 | 0.250 | 0.250 | -0.18 | X |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Ivan De Jesus | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Guillermo Quiroz | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 200.3 | 4.90 | 32 | 0 | X | -4.05 |
| Clay Buchholz | 189.3 | 4.56 | 29 | 0 | X | -2.35 |
| Felix Doubront | 161.0 | 4.86 | 29 | 0 | X | -3.13 |
| Josh Beckett | 127.3 | 5.23 | 21 | 0 | X | -3.57 |
| Aaron Cook | 94.0 | 5.65 | 18 | 0 | X | -3.55 |
| Alfredo Aceves | 84.0 | 5.36 | 0 | 69 | X | -2.60 |
| Franklin Morales | 76.3 | 3.66 | 9 | 28 | X | 0.67 |
| Daniel Bard | 59.3 | 6.22 | 10 | 7 | X | -3.03 |
| Scott Atchison | 50.7 | 1.78 | 0 | 41 | X | 2.66 |
| Vicente Padilla | 49.0 | 4.59 | 0 | 55 | X | -0.64 |
| Mark Melancon | 43.3 | 6.44 | 0 | 40 | X | -2.43 |
| Daisuke Matsuzaka | 43.3 | 7.68 | 10 | 0 | X | -3.69 |
| Junichi Tazawa | 42.0 | 1.50 | 0 | 35 | X | 2.48 |
| Clayton Mortensen | 40.0 | 2.48 | 0 | 25 | X | 1.45 |
| Andrew Miller | 39.7 | 3.18 | 0 | 52 | X | 0.79 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.60 |
| Rich Hill | 18.7 | 1.93 | 0 | 24 | X | 0.92 |
| Craig Breslow | 18.3 | 2.95 | 0 | 21 | X | 0.46 |
| Andrew Bailey | 15.0 | 6.00 | 0 | 18 | X | -0.69 |
| Pedro Beato | 6.7 | 2.70 | 0 | 3 | X | 0.21 |
| Zach Stewart | 5.7 | 22.24 | 2 | 0 | X | -2.41 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Chris Carpenter | 5.7 | 1.59 | 0 | 7 | X | 0.32 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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