| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 610 | 81 | 64 | 0.288 | 0.344 | 0.96 | 2B |
| Mike Aviles | 546 | 56 | 61 | 0.250 | 0.280 | -0.49 | SS |
| Adrian Gonzalez | 527 | 65 | 86 | 0.300 | 0.343 | 3.53 | 1B |
| Cody Ross | 512 | 69 | 80 | 0.268 | 0.330 | 3.67 | RF-LF-DH |
| Jarrod Saltalamacchia | 436 | 55 | 58 | 0.225 | 0.291 | 1.67 | CR-DH |
| David Ortiz | 383 | 68 | 60 | 0.318 | 0.415 | 4.48 | DH |
| Jacoby Ellsbury | 309 | 41 | 26 | 0.277 | 0.320 | -0.19 | CF |
| Daniel Nava | 300 | 36 | 30 | 0.246 | 0.353 | -0.09 | LF |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.55 | 3B |
| Pedro Ciriaco | 257 | 31 | 20 | 0.285 | 0.300 | -0.66 | 3B-2B-SS-DH |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.13 | RF-CF |
| Scott Podsednik | 214 | 19 | 14 | 0.303 | 0.313 | -1.54 | LF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.24 | 3B-1B |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.23 | CR |
| Ryan Lavarnway | 149 | 10 | 12 | 0.161 | 0.215 | -1.18 | CR-DH |
| Nick Punto | 148 | 13 | 10 | 0.200 | 0.297 | -1.05 | 2B |
| Carl Crawford | 125 | 23 | 19 | 0.280 | 0.304 | 1.49 | LF |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.80 | CF |
| Mauro Gomez | 104 | 14 | 17 | 0.281 | 0.327 | 0.82 | 1B |
| Ryan Kalish | 103 | 12 | 6 | 0.229 | 0.272 | -0.52 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | -0.01 | X |
| James Loney | 96 | 4 | 7 | 0.233 | 0.271 | -1.09 | 1B |
| Jose Iglesias | 63 | 5 | 1 | 0.111 | 0.206 | -0.84 | SS |
| Danny Valencia | 22 | 1 | 5 | 0.143 | 0.136 | 0.12 | 3B |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Che-Hsuan Lin | 9 | 1 | 0 | 0.111 | 0.111 | -0.11 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Ivan De Jesus | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Guillermo Quiroz | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 200.3 | 4.90 | 32 | 0 | X | -4.07 |
| Clay Buchholz | 187.7 | 4.22 | 28 | 0 | X | -0.85 |
| Felix Doubront | 161.0 | 4.86 | 29 | 0 | X | -3.14 |
| Josh Beckett | 127.3 | 5.23 | 21 | 0 | X | -3.58 |
| Aaron Cook | 94.0 | 5.65 | 18 | 0 | X | -3.56 |
| Alfredo Aceves | 81.7 | 5.40 | 0 | 68 | X | -2.62 |
| Franklin Morales | 76.3 | 3.66 | 9 | 28 | X | 0.66 |
| Daniel Bard | 59.3 | 6.22 | 10 | 7 | X | -3.04 |
| Scott Atchison | 50.7 | 1.78 | 0 | 41 | X | 2.66 |
| Vicente Padilla | 48.0 | 4.69 | 0 | 54 | X | -0.74 |
| Mark Melancon | 43.3 | 6.44 | 0 | 40 | X | -2.44 |
| Daisuke Matsuzaka | 43.3 | 7.68 | 10 | 0 | X | -3.70 |
| Junichi Tazawa | 42.0 | 1.50 | 0 | 35 | X | 2.48 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.60 |
| Andrew Miller | 39.0 | 3.23 | 0 | 51 | X | 0.72 |
| Clayton Mortensen | 36.7 | 2.45 | 0 | 24 | X | 1.34 |
| Rich Hill | 18.7 | 1.93 | 0 | 24 | X | 0.91 |
| Craig Breslow | 18.3 | 2.95 | 0 | 21 | X | 0.46 |
| Andrew Bailey | 14.0 | 5.79 | 0 | 17 | X | -0.57 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Chris Carpenter | 4.7 | 1.93 | 0 | 6 | X | 0.23 |
| Pedro Beato | 4.3 | 4.15 | 0 | 2 | X | -0.01 |
| Zach Stewart | 3.0 | 27.00 | 1 | 0 | X | -1.61 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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