| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 581 | 78 | 62 | 0.286 | 0.341 | 1.14 | 2B |
| Mike Aviles | 537 | 55 | 61 | 0.250 | 0.281 | -0.35 | SS |
| Adrian Gonzalez | 527 | 65 | 86 | 0.300 | 0.343 | 3.56 | 1B |
| Cody Ross | 483 | 67 | 77 | 0.274 | 0.337 | 3.85 | RF-LF-DH |
| Jarrod Saltalamacchia | 418 | 53 | 56 | 0.229 | 0.292 | 1.69 | CR-DH |
| David Ortiz | 383 | 68 | 60 | 0.318 | 0.415 | 4.50 | DH |
| Jacoby Ellsbury | 305 | 40 | 26 | 0.277 | 0.321 | -0.19 | CF |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.57 | 3B |
| Daniel Nava | 276 | 33 | 29 | 0.238 | 0.348 | 0.07 | LF |
| Pedro Ciriaco | 228 | 29 | 19 | 0.292 | 0.307 | -0.28 | 3B-2B-SS-DH |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.12 | RF-CF |
| Scott Podsednik | 191 | 17 | 13 | 0.294 | 0.304 | -1.31 | LF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.24 | 3B-1B |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.22 | CR |
| Nick Punto | 148 | 13 | 10 | 0.200 | 0.297 | -1.04 | 2B |
| Carl Crawford | 125 | 23 | 19 | 0.280 | 0.304 | 1.49 | LF |
| Ryan Lavarnway | 125 | 10 | 10 | 0.177 | 0.240 | -0.82 | CR-DH |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Ryan Kalish | 103 | 12 | 6 | 0.229 | 0.272 | -0.51 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Mauro Gomez | 88 | 13 | 17 | 0.309 | 0.352 | 1.10 | 1B |
| James Loney | 82 | 4 | 6 | 0.253 | 0.280 | -0.86 | 1B |
| Jose Iglesias | 48 | 5 | 1 | 0.128 | 0.250 | -0.49 | SS |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Danny Valencia | 9 | 0 | 1 | 0.125 | 0.111 | -0.11 | 3B |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 6 | 1 | 0 | 0.167 | 0.167 | -0.04 | X |
| Ivan De Jesus | 6 | 0 | 0 | 0.000 | 0.000 | -0.14 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Guillermo Quiroz | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 187.3 | 4.90 | 30 | 0 | X | -3.81 |
| Clay Buchholz | 181.7 | 4.16 | 27 | 0 | X | -0.56 |
| Felix Doubront | 147.0 | 5.08 | 27 | 0 | X | -3.61 |
| Josh Beckett | 127.3 | 5.23 | 21 | 0 | X | -3.57 |
| Aaron Cook | 87.7 | 4.93 | 16 | 0 | X | -1.84 |
| Alfredo Aceves | 77.3 | 5.00 | 0 | 66 | X | -1.76 |
| Franklin Morales | 76.3 | 3.66 | 9 | 28 | X | 0.67 |
| Daniel Bard | 58.3 | 6.33 | 10 | 6 | X | -3.13 |
| Scott Atchison | 48.3 | 1.86 | 0 | 39 | X | 2.44 |
| Vicente Padilla | 47.0 | 4.79 | 0 | 53 | X | -0.83 |
| Daisuke Matsuzaka | 43.3 | 7.68 | 10 | 0 | X | -3.70 |
| Mark Melancon | 40.0 | 6.97 | 0 | 37 | X | -2.75 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.60 |
| Junichi Tazawa | 39.0 | 1.62 | 0 | 32 | X | 2.20 |
| Andrew Miller | 38.3 | 3.29 | 0 | 50 | X | 0.66 |
| Clayton Mortensen | 35.3 | 2.04 | 0 | 22 | X | 1.64 |
| Rich Hill | 17.7 | 2.04 | 0 | 22 | X | 0.82 |
| Craig Breslow | 16.3 | 3.31 | 0 | 19 | X | 0.28 |
| Andrew Bailey | 12.0 | 6.75 | 0 | 15 | X | -0.76 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Chris Carpenter | 4.3 | 2.08 | 0 | 5 | X | 0.20 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Zach Stewart | 3.0 | 27.00 | 1 | 0 | X | -1.61 |
| Pedro Beato | 2.0 | 9.00 | 0 | 1 | X | -0.23 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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