| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 548 | 76 | 58 | 0.289 | 0.345 | 1.28 | 2B |
| Adrian Gonzalez | 527 | 65 | 86 | 0.300 | 0.343 | 3.56 | 1B |
| Mike Aviles | 515 | 54 | 60 | 0.251 | 0.282 | -0.05 | SS |
| Cody Ross | 442 | 60 | 75 | 0.280 | 0.344 | 3.86 | RF-LF-DH |
| Jarrod Saltalamacchia | 389 | 48 | 53 | 0.225 | 0.285 | 1.53 | CR-DH |
| David Ortiz | 383 | 68 | 60 | 0.318 | 0.415 | 4.50 | DH |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.57 | 3B |
| Jacoby Ellsbury | 261 | 37 | 18 | 0.257 | 0.299 | -0.32 | CF |
| Daniel Nava | 248 | 32 | 27 | 0.249 | 0.367 | 0.41 | LF |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.12 | RF-CF |
| Pedro Ciriaco | 189 | 24 | 17 | 0.301 | 0.312 | -0.11 | 3B-2B-SS-DH |
| Scott Podsednik | 169 | 17 | 13 | 0.321 | 0.325 | -0.79 | LF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.24 | 3B-1B |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.22 | CR |
| Nick Punto | 148 | 13 | 10 | 0.200 | 0.297 | -1.04 | 2B |
| Carl Crawford | 125 | 23 | 19 | 0.280 | 0.304 | 1.49 | LF |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Ryan Kalish | 99 | 12 | 6 | 0.228 | 0.273 | -0.42 | CF |
| Ryan Lavarnway | 92 | 6 | 3 | 0.169 | 0.239 | -1.20 | CR-DH |
| Mauro Gomez | 73 | 10 | 11 | 0.299 | 0.342 | 0.50 | 1B |
| James Loney | 45 | 2 | 4 | 0.273 | 0.289 | -0.42 | 1B |
| Jose Iglesias | 25 | 0 | 0 | 0.091 | 0.160 | -0.58 | SS |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Danny Valencia | 9 | 0 | 1 | 0.125 | 0.111 | -0.11 | 3B |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 6 | 1 | 0 | 0.167 | 0.167 | -0.04 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Ivan De Jesus | 2 | 0 | 0 | 0.000 | 0.000 | -0.05 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 175.0 | 4.94 | 28 | 0 | X | -3.71 |
| Clay Buchholz | 167.7 | 4.46 | 25 | 0 | X | -1.67 |
| Felix Doubront | 134.7 | 5.21 | 25 | 0 | X | -3.72 |
| Josh Beckett | 127.3 | 5.23 | 21 | 0 | X | -3.57 |
| Aaron Cook | 76.7 | 5.17 | 14 | 0 | X | -2.03 |
| Franklin Morales | 76.3 | 3.66 | 9 | 28 | X | 0.67 |
| Alfredo Aceves | 74.3 | 4.48 | 0 | 64 | X | -0.78 |
| Daniel Bard | 58.0 | 5.59 | 10 | 4 | X | -2.11 |
| Vicente Padilla | 46.3 | 4.47 | 0 | 49 | X | -0.47 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.22 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.60 |
| Mark Melancon | 38.0 | 7.11 | 0 | 35 | X | -2.73 |
| Andrew Miller | 37.3 | 3.37 | 0 | 47 | X | 0.57 |
| Daisuke Matsuzaka | 35.0 | 7.20 | 8 | 0 | X | -2.59 |
| Clayton Mortensen | 34.0 | 1.59 | 0 | 20 | X | 1.94 |
| Junichi Tazawa | 33.3 | 1.62 | 0 | 26 | X | 1.87 |
| Rich Hill | 16.0 | 2.25 | 0 | 20 | X | 0.66 |
| Craig Breslow | 12.3 | 4.38 | 0 | 15 | X | -0.10 |
| Andrew Bailey | 7.7 | 4.70 | 0 | 10 | X | -0.12 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Zach Stewart | 3.0 | 27.00 | 1 | 0 | X | -1.61 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Pedro Beato | 2.0 | 9.00 | 0 | 1 | X | -0.23 |
| Chris Carpenter | 1.3 | 0.00 | 0 | 2 | X | 0.13 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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