| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 573 | 80 | 89 | 0.208 | 0.340 | 4.18 | DH-1B |
| Alex Rios | 557 | 81 | 84 | 0.292 | 0.323 | 4.14 | RF |
| Alexei Ramirez | 537 | 55 | 65 | 0.274 | 0.294 | -0.11 | SS |
| Alejandro de Aza | 518 | 74 | 46 | 0.281 | 0.346 | 0.34 | CF-LF |
| Gordon Beckham | 513 | 55 | 53 | 0.232 | 0.283 | -0.81 | 2B |
| Paul Konerko | 512 | 64 | 65 | 0.311 | 0.381 | 1.42 | 1B-DH |
| Dayan Viciedo | 474 | 56 | 60 | 0.255 | 0.293 | 0.96 | LF-DH |
| A.J. Pierzynski | 448 | 62 | 72 | 0.286 | 0.330 | 3.46 | CR |
| Kevin Youkilis | 254 | 39 | 38 | 0.242 | 0.362 | 2.07 | 3B-1B |
| Tyler Flowers | 138 | 17 | 13 | 0.234 | 0.304 | -0.12 | CR |
| Orlando Hudson | 130 | 7 | 12 | 0.188 | 0.246 | -1.08 | 2B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.96 | 3B |
| Dewayne Wise | 104 | 14 | 16 | 0.296 | 0.337 | 0.69 | LF |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.83 | X |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.82 | SS-3B |
| Jordan Danks | 62 | 6 | 4 | 0.228 | 0.258 | -0.42 | LF-CF |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.58 | LF |
| Ray Olmedo | 30 | 4 | 1 | 0.207 | 0.200 | -0.19 | 3B |
| Jose Lopez | 15 | 0 | 0 | 0.214 | 0.267 | -0.36 | 3B-DH-1B |
| Dan Johnson | 9 | 2 | 1 | 0.429 | 0.556 | 0.10 | X |
| Hector Gimenez | 4 | 1 | 0 | 0.500 | 0.500 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 187.0 | 3.22 | 27 | 0 | X | 3.50 |
| Chris Sale | 169.0 | 2.88 | 25 | 1 | X | 4.53 |
| Gavin Floyd | 138.3 | 4.55 | 24 | 0 | X | -1.71 |
| Jose Quintana | 115.0 | 3.68 | 18 | 2 | X | 0.93 |
| Philip Humber | 101.0 | 6.50 | 16 | 9 | X | -5.84 |
| Nate Jones | 58.7 | 2.76 | 0 | 55 | X | 1.73 |
| Matt Thornton | 58.0 | 3.41 | 0 | 65 | X | 0.83 |
| Hector Santiago | 57.3 | 3.45 | 2 | 36 | X | 0.77 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.10 |
| Addison Reed | 50.3 | 4.65 | 0 | 55 | X | -0.73 |
| Dylan Axelrod | 48.3 | 5.03 | 7 | 5 | X | -1.13 |
| Francisco Liriano | 40.7 | 5.09 | 8 | 0 | X | -1.01 |
| Jesse Crain | 38.7 | 2.56 | 0 | 44 | X | 1.32 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.38 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.49 |
| Brett Myers | 21.7 | 4.15 | 0 | 25 | X | -0.06 |
| Brian Omogrosso | 12.0 | 3.00 | 0 | 8 | X | 0.29 |
| Leyson Septimo | 10.3 | 5.23 | 0 | 16 | X | -0.29 |
| Donnie Veal | 8.7 | 2.08 | 0 | 13 | X | 0.39 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | 0.00 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.30 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Dewayne Wise | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Deunte Heath | 0.7 | 0.00 | 0 | 1 | X | 0.06 |
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