| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 569 | 79 | 89 | 0.207 | 0.339 | 4.15 | DH-1B |
| Alex Rios | 540 | 79 | 78 | 0.295 | 0.326 | 3.68 | RF |
| Alexei Ramirez | 524 | 54 | 62 | 0.271 | 0.292 | -0.24 | SS |
| Alejandro de Aza | 508 | 73 | 46 | 0.279 | 0.341 | 0.45 | CF-LF |
| Gordon Beckham | 497 | 54 | 52 | 0.231 | 0.282 | -0.65 | 2B |
| Paul Konerko | 496 | 62 | 63 | 0.307 | 0.377 | 1.37 | 1B-DH |
| Dayan Viciedo | 459 | 54 | 59 | 0.256 | 0.294 | 0.98 | LF-DH |
| A.J. Pierzynski | 432 | 59 | 71 | 0.284 | 0.329 | 3.41 | CR |
| Kevin Youkilis | 250 | 38 | 38 | 0.245 | 0.364 | 2.05 | 3B-1B |
| Tyler Flowers | 134 | 16 | 11 | 0.230 | 0.291 | -0.34 | CR |
| Orlando Hudson | 129 | 7 | 12 | 0.188 | 0.240 | -1.06 | 2B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.97 | 3B |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.83 | X |
| Dewayne Wise | 87 | 12 | 15 | 0.293 | 0.333 | 0.77 | LF |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.82 | SS-3B |
| Jordan Danks | 61 | 6 | 4 | 0.232 | 0.262 | -0.40 | LF-CF |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.58 | LF |
| Ray Olmedo | 21 | 4 | 1 | 0.286 | 0.286 | 0.03 | 3B |
| Jose Lopez | 7 | 0 | 0 | 0.333 | 0.429 | -0.17 | 3B-DH-1B |
| Dan Johnson | 7 | 2 | 1 | 0.500 | 0.571 | 0.15 | X |
| Hector Gimenez | 4 | 1 | 0 | 0.500 | 0.500 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 181.0 | 3.28 | 26 | 0 | X | 3.18 |
| Chris Sale | 163.0 | 2.93 | 24 | 1 | X | 4.21 |
| Gavin Floyd | 138.3 | 4.55 | 24 | 0 | X | -1.68 |
| Jose Quintana | 115.0 | 3.68 | 18 | 2 | X | 0.95 |
| Philip Humber | 101.0 | 6.50 | 16 | 9 | X | -5.82 |
| Nate Jones | 55.7 | 2.91 | 0 | 53 | X | 1.46 |
| Matt Thornton | 54.7 | 3.62 | 0 | 61 | X | 0.53 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.09 |
| Hector Santiago | 53.3 | 3.71 | 1 | 36 | X | 0.40 |
| Dylan Axelrod | 48.3 | 5.03 | 7 | 5 | X | -1.12 |
| Addison Reed | 47.3 | 3.99 | 0 | 52 | X | 0.04 |
| Jesse Crain | 36.7 | 2.70 | 0 | 41 | X | 1.14 |
| Francisco Liriano | 35.7 | 4.54 | 7 | 0 | X | -0.42 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.38 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.48 |
| Brett Myers | 20.0 | 3.15 | 0 | 22 | X | 0.41 |
| Brian Omogrosso | 10.0 | 3.60 | 0 | 7 | X | 0.10 |
| Leyson Septimo | 10.0 | 5.40 | 0 | 15 | X | -0.32 |
| Donnie Veal | 8.0 | 2.25 | 0 | 11 | X | 0.33 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | 0.00 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.30 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Dewayne Wise | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Deunte Heath | 0.7 | 0.00 | 0 | 1 | X | 0.06 |
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