| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 527 | 73 | 55 | 0.290 | 0.345 | 1.16 | 2B |
| Adrian Gonzalez | 527 | 65 | 86 | 0.300 | 0.343 | 3.57 | 1B |
| Mike Aviles | 499 | 52 | 60 | 0.256 | 0.283 | 0.13 | SS |
| Cody Ross | 422 | 58 | 71 | 0.274 | 0.336 | 3.71 | RF-LF-DH |
| David Ortiz | 383 | 68 | 60 | 0.318 | 0.415 | 4.51 | DH |
| Jarrod Saltalamacchia | 378 | 48 | 53 | 0.231 | 0.286 | 1.80 | CR-DH |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.58 | 3B |
| Daniel Nava | 247 | 32 | 27 | 0.250 | 0.368 | 0.44 | LF |
| Jacoby Ellsbury | 240 | 34 | 16 | 0.262 | 0.304 | -0.34 | CF |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.11 | RF-CF |
| Pedro Ciriaco | 172 | 23 | 16 | 0.317 | 0.326 | 0.09 | 3B-2B-SS-DH |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.25 | 3B-1B |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.22 | CR |
| Scott Podsednik | 149 | 17 | 12 | 0.336 | 0.342 | -0.43 | LF-CF |
| Nick Punto | 148 | 13 | 10 | 0.200 | 0.297 | -1.03 | 2B |
| Carl Crawford | 125 | 23 | 19 | 0.280 | 0.304 | 1.50 | LF |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Ryan Kalish | 94 | 11 | 6 | 0.216 | 0.255 | -0.41 | CF |
| Ryan Lavarnway | 76 | 4 | 2 | 0.174 | 0.237 | -1.14 | CR-DH |
| Mauro Gomez | 65 | 9 | 8 | 0.288 | 0.338 | 0.27 | 1B |
| James Loney | 29 | 2 | 4 | 0.286 | 0.310 | -0.05 | 1B |
| Jose Iglesias | 18 | 0 | 0 | 0.000 | 0.111 | -0.42 | SS |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Danny Valencia | 9 | 0 | 1 | 0.125 | 0.111 | -0.10 | 3B |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 6 | 1 | 0 | 0.167 | 0.167 | -0.03 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Ivan De Jesus | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 169.0 | 4.95 | 27 | 0 | X | -3.64 |
| Clay Buchholz | 159.0 | 4.47 | 24 | 0 | X | -1.64 |
| Felix Doubront | 130.7 | 5.03 | 24 | 0 | X | -3.04 |
| Josh Beckett | 127.3 | 5.23 | 21 | 0 | X | -3.57 |
| Franklin Morales | 76.3 | 3.66 | 9 | 28 | X | 0.67 |
| Aaron Cook | 70.7 | 5.35 | 13 | 0 | X | -2.18 |
| Alfredo Aceves | 70.3 | 4.73 | 0 | 62 | X | -1.16 |
| Daniel Bard | 57.0 | 5.37 | 10 | 3 | X | -1.78 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.23 |
| Vicente Padilla | 44.3 | 4.47 | 0 | 47 | X | -0.45 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.60 |
| Mark Melancon | 36.0 | 7.50 | 0 | 34 | X | -2.92 |
| Andrew Miller | 35.7 | 3.53 | 0 | 45 | X | 0.41 |
| Daisuke Matsuzaka | 33.7 | 6.15 | 7 | 0 | X | -1.66 |
| Junichi Tazawa | 32.3 | 1.67 | 0 | 24 | X | 1.78 |
| Clayton Mortensen | 32.0 | 1.69 | 0 | 19 | X | 1.75 |
| Rich Hill | 15.0 | 2.40 | 0 | 19 | X | 0.57 |
| Craig Breslow | 12.0 | 4.50 | 0 | 14 | X | -0.13 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Andrew Bailey | 5.7 | 1.59 | 0 | 8 | X | 0.32 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Zach Stewart | 3.0 | 27.00 | 1 | 0 | X | -1.61 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Pedro Beato | 2.0 | 9.00 | 0 | 1 | X | -0.23 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
| Chris Carpenter | 0.3 | 0.00 | 0 | 1 | X | 0.03 |
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