| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 563 | 78 | 89 | 0.205 | 0.337 | 4.21 | DH-1B |
| Alex Rios | 530 | 78 | 77 | 0.297 | 0.328 | 3.73 | RF |
| Alexei Ramirez | 514 | 53 | 61 | 0.270 | 0.292 | -0.20 | SS |
| Alejandro de Aza | 494 | 72 | 44 | 0.281 | 0.344 | 0.48 | CF-LF |
| Gordon Beckham | 491 | 53 | 49 | 0.229 | 0.279 | -0.91 | 2B |
| Paul Konerko | 486 | 62 | 61 | 0.309 | 0.379 | 1.41 | 1B-DH |
| Dayan Viciedo | 453 | 53 | 58 | 0.255 | 0.291 | 0.93 | LF-DH |
| A.J. Pierzynski | 424 | 57 | 71 | 0.285 | 0.330 | 3.40 | CR |
| Kevin Youkilis | 240 | 36 | 38 | 0.240 | 0.358 | 2.09 | 3B-1B |
| Tyler Flowers | 127 | 15 | 10 | 0.231 | 0.283 | -0.38 | CR |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.96 | 3B |
| Orlando Hudson | 122 | 7 | 12 | 0.191 | 0.246 | -0.89 | 2B |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.83 | X |
| Dewayne Wise | 80 | 11 | 13 | 0.280 | 0.325 | 0.63 | LF |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.82 | SS-3B |
| Jordan Danks | 59 | 6 | 4 | 0.241 | 0.271 | -0.35 | LF-CF |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.58 | LF |
| Ray Olmedo | 18 | 3 | 0 | 0.278 | 0.278 | -0.11 | 3B |
| Jose Lopez | 4 | 0 | 0 | 0.500 | 0.500 | -0.09 | 3B-DH-1B |
| Dan Johnson | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Hector Gimenez | 1 | 1 | 0 | 1.000 | 1.000 | 0.08 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 181.0 | 3.28 | 26 | 0 | X | 3.13 |
| Chris Sale | 157.0 | 2.81 | 23 | 1 | X | 4.45 |
| Gavin Floyd | 138.3 | 4.55 | 24 | 0 | X | -1.72 |
| Jose Quintana | 113.7 | 3.17 | 17 | 2 | X | 2.27 |
| Philip Humber | 100.7 | 5.81 | 16 | 8 | X | -4.20 |
| Nate Jones | 54.0 | 3.00 | 0 | 51 | X | 1.29 |
| Matt Thornton | 53.7 | 3.52 | 0 | 60 | X | 0.63 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.10 |
| Hector Santiago | 48.3 | 3.91 | 0 | 36 | X | 0.13 |
| Addison Reed | 46.3 | 4.08 | 0 | 51 | X | -0.06 |
| Dylan Axelrod | 45.7 | 4.93 | 7 | 4 | X | -0.96 |
| Jesse Crain | 36.3 | 2.72 | 0 | 40 | X | 1.10 |
| Francisco Liriano | 35.7 | 4.54 | 7 | 0 | X | -0.43 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.38 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.49 |
| Brett Myers | 18.7 | 3.37 | 0 | 20 | X | 0.28 |
| Leyson Septimo | 9.3 | 5.79 | 0 | 13 | X | -0.38 |
| Donnie Veal | 7.7 | 2.35 | 0 | 10 | X | 0.30 |
| Brian Omogrosso | 6.7 | 4.05 | 0 | 6 | X | 0.00 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | 0.00 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.30 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Deunte Heath | 0.7 | 0.00 | 0 | 1 | X | 0.06 |
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