| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 554 | 78 | 89 | 0.206 | 0.338 | 4.42 | DH-1B |
| Alex Rios | 517 | 77 | 77 | 0.301 | 0.333 | 3.93 | RF |
| Alexei Ramirez | 503 | 53 | 59 | 0.267 | 0.288 | -0.14 | SS |
| Alejandro de Aza | 494 | 72 | 44 | 0.281 | 0.344 | 0.49 | CF-LF |
| Gordon Beckham | 480 | 53 | 48 | 0.232 | 0.281 | -0.75 | 2B |
| Paul Konerko | 473 | 61 | 59 | 0.315 | 0.387 | 1.41 | 1B-DH |
| Dayan Viciedo | 440 | 51 | 58 | 0.255 | 0.291 | 1.03 | LF-DH |
| A.J. Pierzynski | 412 | 56 | 70 | 0.288 | 0.333 | 3.48 | CR |
| Kevin Youkilis | 231 | 35 | 38 | 0.250 | 0.368 | 2.20 | 3B-1B |
| Tyler Flowers | 127 | 15 | 10 | 0.231 | 0.283 | -0.38 | CR |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.96 | 3B |
| Orlando Hudson | 121 | 7 | 11 | 0.183 | 0.240 | -0.97 | 2B |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.83 | X |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.82 | SS-3B |
| Dewayne Wise | 67 | 10 | 12 | 0.292 | 0.313 | 0.72 | LF |
| Jordan Danks | 59 | 6 | 4 | 0.241 | 0.271 | -0.35 | LF-CF |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.58 | LF |
| Ray Olmedo | 18 | 3 | 0 | 0.278 | 0.278 | -0.11 | 3B |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 175.0 | 3.09 | 25 | 0 | X | 3.77 |
| Chris Sale | 157.0 | 2.81 | 23 | 1 | X | 4.40 |
| Gavin Floyd | 138.3 | 4.55 | 24 | 0 | X | -1.76 |
| Jose Quintana | 110.0 | 2.86 | 16 | 2 | X | 2.94 |
| Philip Humber | 99.7 | 5.87 | 16 | 7 | X | -4.33 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.12 |
| Matt Thornton | 52.7 | 3.42 | 0 | 59 | X | 0.73 |
| Nate Jones | 50.7 | 3.20 | 0 | 49 | X | 0.96 |
| Hector Santiago | 47.3 | 3.99 | 0 | 35 | X | 0.02 |
| Addison Reed | 46.0 | 3.91 | 0 | 50 | X | 0.10 |
| Dylan Axelrod | 45.7 | 4.93 | 7 | 4 | X | -0.98 |
| Jesse Crain | 35.3 | 2.55 | 0 | 39 | X | 1.21 |
| Francisco Liriano | 31.7 | 4.26 | 6 | 0 | X | -0.19 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.39 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.50 |
| Brett Myers | 18.7 | 3.37 | 0 | 20 | X | 0.28 |
| Leyson Septimo | 9.0 | 6.00 | 0 | 12 | X | -0.42 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Donnie Veal | 6.3 | 2.84 | 0 | 8 | X | 0.17 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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