| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 529 | 74 | 85 | 0.205 | 0.338 | 4.20 | DH-1B |
| Alex Rios | 494 | 73 | 74 | 0.301 | 0.330 | 3.77 | RF |
| Alejandro de Aza | 494 | 72 | 44 | 0.281 | 0.344 | 0.51 | CF-LF |
| Alexei Ramirez | 481 | 49 | 53 | 0.261 | 0.281 | -0.65 | SS |
| Gordon Beckham | 461 | 52 | 45 | 0.230 | 0.280 | -0.70 | 2B |
| Paul Konerko | 448 | 59 | 57 | 0.312 | 0.384 | 1.60 | 1B-DH |
| Dayan Viciedo | 425 | 49 | 57 | 0.252 | 0.289 | 1.09 | LF-DH |
| A.J. Pierzynski | 400 | 56 | 69 | 0.296 | 0.343 | 3.68 | CR |
| Kevin Youkilis | 207 | 32 | 34 | 0.246 | 0.367 | 2.04 | 3B-1B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.96 | 3B |
| Orlando Hudson | 121 | 7 | 11 | 0.183 | 0.240 | -0.97 | 2B |
| Tyler Flowers | 117 | 13 | 7 | 0.222 | 0.282 | -0.66 | CR |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.82 | X |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.81 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.57 | LF |
| Jordan Danks | 51 | 5 | 3 | 0.265 | 0.275 | -0.36 | LF-CF |
| Dewayne Wise | 40 | 5 | 11 | 0.350 | 0.350 | 0.74 | LF |
| Ray Olmedo | 14 | 2 | 0 | 0.214 | 0.214 | -0.12 | 3B |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 168.0 | 3.11 | 24 | 0 | X | 3.50 |
| Chris Sale | 153.0 | 2.65 | 22 | 1 | X | 4.83 |
| Gavin Floyd | 136.3 | 4.56 | 23 | 0 | X | -1.76 |
| Jose Quintana | 104.3 | 2.76 | 15 | 2 | X | 3.02 |
| Philip Humber | 95.3 | 5.76 | 16 | 5 | X | -3.91 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.13 |
| Matt Thornton | 51.0 | 3.53 | 0 | 57 | X | 0.56 |
| Nate Jones | 49.0 | 3.31 | 0 | 46 | X | 0.79 |
| Addison Reed | 44.3 | 3.45 | 0 | 48 | X | 0.57 |
| Hector Santiago | 43.3 | 3.95 | 0 | 34 | X | 0.06 |
| Dylan Axelrod | 38.3 | 5.63 | 6 | 4 | X | -1.46 |
| Jesse Crain | 34.3 | 2.62 | 0 | 38 | X | 1.11 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.40 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.50 |
| Francisco Liriano | 26.7 | 4.39 | 5 | 0 | X | -0.24 |
| Brett Myers | 15.3 | 2.93 | 0 | 18 | X | 0.38 |
| Leyson Septimo | 9.0 | 6.00 | 0 | 12 | X | -0.42 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Donnie Veal | 5.0 | 1.80 | 0 | 6 | X | 0.26 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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