| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 521 | 65 | 85 | 0.301 | 0.345 | 3.62 | 1B |
| Dustin Pedroia | 474 | 64 | 47 | 0.276 | 0.331 | 0.62 | 2B |
| Mike Aviles | 456 | 49 | 54 | 0.253 | 0.283 | 0.20 | SS |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.40 | DH |
| Cody Ross | 374 | 54 | 62 | 0.272 | 0.337 | 3.47 | RF-LF-DH |
| Jarrod Saltalamacchia | 352 | 45 | 49 | 0.229 | 0.287 | 1.67 | CR-DH |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.58 | 3B |
| Daniel Nava | 247 | 32 | 27 | 0.250 | 0.368 | 0.44 | LF |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.11 | RF-CF |
| Jacoby Ellsbury | 191 | 24 | 11 | 0.249 | 0.298 | -0.77 | CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.25 | 3B-1B |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.21 | CR |
| Nick Punto | 148 | 13 | 10 | 0.200 | 0.297 | -1.03 | 2B |
| Carl Crawford | 125 | 23 | 19 | 0.280 | 0.304 | 1.50 | LF |
| Pedro Ciriaco | 120 | 12 | 12 | 0.328 | 0.333 | -0.27 | 3B-2B-SS-DH |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Scott Podsednik | 101 | 13 | 9 | 0.366 | 0.376 | -0.04 | LF-CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Ryan Kalish | 85 | 11 | 5 | 0.203 | 0.247 | -0.30 | CF |
| Ryan Lavarnway | 37 | 1 | 1 | 0.147 | 0.216 | -0.65 | CR-DH |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.09 | 1B |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Danny Valencia | 9 | 0 | 1 | 0.125 | 0.111 | -0.10 | 3B |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 154.0 | 4.97 | 25 | 0 | X | -3.39 |
| Clay Buchholz | 145.0 | 4.47 | 22 | 0 | X | -1.51 |
| Josh Beckett | 127.3 | 5.23 | 21 | 0 | X | -3.59 |
| Felix Doubront | 122.7 | 4.70 | 22 | 0 | X | -1.93 |
| Franklin Morales | 73.7 | 3.54 | 8 | 28 | X | 0.82 |
| Aaron Cook | 62.0 | 4.79 | 11 | 0 | X | -1.11 |
| Alfredo Aceves | 61.7 | 3.94 | 0 | 57 | X | 0.12 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.56 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.22 |
| Vicente Padilla | 40.0 | 4.50 | 0 | 42 | X | -0.45 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.59 |
| Andrew Miller | 32.3 | 2.78 | 0 | 41 | X | 0.93 |
| Mark Melancon | 31.3 | 6.89 | 0 | 29 | X | -2.10 |
| Clayton Mortensen | 31.3 | 1.72 | 0 | 16 | X | 1.68 |
| Junichi Tazawa | 25.0 | 1.44 | 0 | 19 | X | 1.51 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.41 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.44 |
| Craig Breslow | 7.3 | 2.45 | 0 | 9 | X | 0.27 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Andrew Bailey | 1.3 | 0.00 | 0 | 3 | X | 0.13 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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