| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 508 | 64 | 84 | 0.308 | 0.352 | 3.68 | 1B |
| Dustin Pedroia | 460 | 63 | 47 | 0.280 | 0.335 | 0.81 | 2B |
| Mike Aviles | 448 | 49 | 53 | 0.255 | 0.283 | 0.25 | SS |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.38 | DH |
| Cody Ross | 366 | 53 | 62 | 0.272 | 0.336 | 3.53 | RF-LF-DH |
| Jarrod Saltalamacchia | 341 | 43 | 47 | 0.226 | 0.282 | 1.49 | CR-DH |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.56 | 3B |
| Daniel Nava | 242 | 32 | 27 | 0.251 | 0.372 | 0.55 | LF |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.12 | RF-CF |
| Jacoby Ellsbury | 178 | 24 | 11 | 0.256 | 0.309 | -0.48 | CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.24 | 3B-1B |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.22 | CR |
| Nick Punto | 145 | 13 | 10 | 0.197 | 0.297 | -0.97 | 2B |
| Carl Crawford | 121 | 23 | 19 | 0.281 | 0.306 | 1.59 | LF |
| Pedro Ciriaco | 109 | 12 | 12 | 0.343 | 0.349 | -0.02 | 3B-2B-SS-DH |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Scott Podsednik | 89 | 12 | 9 | 0.358 | 0.371 | 0.13 | LF-CF |
| Ryan Kalish | 85 | 11 | 5 | 0.203 | 0.247 | -0.30 | CF |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.09 | 1B |
| Ryan Lavarnway | 30 | 0 | 0 | 0.107 | 0.167 | -0.70 | CR-DH |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Danny Valencia | 9 | 0 | 1 | 0.125 | 0.111 | -0.11 | 3B |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 154.0 | 4.97 | 25 | 0 | X | -3.36 |
| Clay Buchholz | 139.7 | 4.19 | 21 | 0 | X | -0.51 |
| Felix Doubront | 122.7 | 4.70 | 22 | 0 | X | -1.90 |
| Josh Beckett | 121.3 | 5.19 | 20 | 0 | X | -3.28 |
| Franklin Morales | 73.7 | 3.54 | 8 | 28 | X | 0.84 |
| Alfredo Aceves | 60.7 | 4.01 | 0 | 56 | X | 0.04 |
| Aaron Cook | 57.0 | 4.58 | 10 | 0 | X | -0.73 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.55 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.23 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.60 |
| Vicente Padilla | 39.0 | 4.62 | 0 | 41 | X | -0.53 |
| Andrew Miller | 31.0 | 2.90 | 0 | 40 | X | 0.82 |
| Mark Melancon | 30.3 | 7.12 | 0 | 28 | X | -2.19 |
| Clayton Mortensen | 29.3 | 1.84 | 0 | 15 | X | 1.50 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.41 |
| Junichi Tazawa | 21.7 | 1.66 | 0 | 17 | X | 1.20 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.45 |
| Craig Breslow | 7.3 | 2.45 | 0 | 9 | X | 0.27 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Andrew Bailey | 1.3 | 0.00 | 0 | 3 | X | 0.13 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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