| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 508 | 70 | 82 | 0.206 | 0.339 | 3.96 | DH-1B |
| Alejandro de Aza | 494 | 72 | 44 | 0.281 | 0.344 | 0.51 | CF-LF |
| Alex Rios | 473 | 70 | 72 | 0.306 | 0.336 | 3.74 | RF |
| Alexei Ramirez | 463 | 47 | 51 | 0.262 | 0.281 | -0.65 | SS |
| Gordon Beckham | 443 | 48 | 43 | 0.227 | 0.275 | -0.91 | 2B |
| Paul Konerko | 427 | 57 | 54 | 0.315 | 0.386 | 1.57 | 1B-DH |
| Dayan Viciedo | 407 | 48 | 56 | 0.256 | 0.295 | 1.30 | LF-DH |
| A.J. Pierzynski | 385 | 54 | 67 | 0.296 | 0.343 | 3.61 | CR |
| Kevin Youkilis | 189 | 29 | 29 | 0.247 | 0.365 | 1.62 | 3B-1B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.96 | 3B |
| Orlando Hudson | 121 | 7 | 11 | 0.183 | 0.240 | -0.97 | 2B |
| Tyler Flowers | 113 | 13 | 7 | 0.221 | 0.283 | -0.57 | CR |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.82 | X |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.81 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.57 | LF |
| Jordan Danks | 51 | 5 | 3 | 0.265 | 0.275 | -0.36 | LF-CF |
| Dewayne Wise | 18 | 3 | 7 | 0.333 | 0.333 | 0.62 | LF |
| Ray Olmedo | 11 | 1 | 0 | 0.182 | 0.182 | -0.15 | 3B |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 162.7 | 3.04 | 23 | 0 | X | 3.65 |
| Chris Sale | 145.3 | 2.72 | 21 | 1 | X | 4.34 |
| Gavin Floyd | 134.0 | 4.43 | 22 | 0 | X | -1.34 |
| Jose Quintana | 97.3 | 2.77 | 14 | 2 | X | 2.79 |
| Philip Humber | 94.0 | 5.84 | 16 | 4 | X | -4.03 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.13 |
| Matt Thornton | 49.3 | 3.65 | 0 | 55 | X | 0.41 |
| Nate Jones | 48.3 | 3.35 | 0 | 44 | X | 0.74 |
| Addison Reed | 42.3 | 3.61 | 0 | 46 | X | 0.38 |
| Hector Santiago | 40.3 | 3.57 | 0 | 33 | X | 0.41 |
| Dylan Axelrod | 38.3 | 5.63 | 6 | 4 | X | -1.46 |
| Jesse Crain | 32.7 | 1.93 | 0 | 36 | X | 1.58 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.40 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.50 |
| Francisco Liriano | 20.7 | 4.79 | 4 | 0 | X | -0.38 |
| Brett Myers | 12.3 | 0.73 | 0 | 14 | X | 0.94 |
| Leyson Septimo | 9.0 | 6.00 | 0 | 12 | X | -0.42 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Donnie Veal | 3.7 | 0.00 | 0 | 3 | X | 0.34 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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