| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 491 | 68 | 79 | 0.208 | 0.340 | 3.84 | DH-1B |
| Alejandro de Aza | 482 | 70 | 43 | 0.283 | 0.344 | 0.48 | CF-LF |
| Alex Rios | 456 | 69 | 68 | 0.314 | 0.344 | 3.61 | RF |
| Alexei Ramirez | 448 | 44 | 50 | 0.262 | 0.281 | -0.71 | SS |
| Gordon Beckham | 435 | 48 | 42 | 0.226 | 0.276 | -0.83 | 2B |
| Paul Konerko | 423 | 56 | 53 | 0.316 | 0.388 | 1.45 | 1B-DH |
| Dayan Viciedo | 392 | 44 | 53 | 0.249 | 0.286 | 0.92 | LF-DH |
| A.J. Pierzynski | 368 | 51 | 67 | 0.299 | 0.348 | 3.70 | CR |
| Kevin Youkilis | 172 | 27 | 29 | 0.245 | 0.366 | 1.82 | 3B-1B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.96 | 3B |
| Orlando Hudson | 119 | 7 | 11 | 0.178 | 0.235 | -0.92 | 2B |
| Tyler Flowers | 109 | 12 | 6 | 0.220 | 0.284 | -0.69 | CR |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.82 | X |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.81 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.57 | LF |
| Jordan Danks | 51 | 5 | 3 | 0.265 | 0.275 | -0.36 | LF-CF |
| Ray Olmedo | 7 | 1 | 0 | 0.286 | 0.286 | -0.06 | 3B |
| Dewayne Wise | 4 | 1 | 1 | 0.500 | 0.500 | 0.12 | LF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 162.7 | 3.04 | 23 | 0 | X | 3.66 |
| Chris Sale | 138.7 | 2.60 | 20 | 1 | X | 4.56 |
| Gavin Floyd | 128.0 | 4.43 | 21 | 0 | X | -1.26 |
| Philip Humber | 92.0 | 5.87 | 16 | 2 | X | -4.00 |
| Jose Quintana | 90.7 | 2.78 | 13 | 2 | X | 2.60 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.12 |
| Matt Thornton | 48.7 | 3.70 | 0 | 54 | X | 0.35 |
| Nate Jones | 48.3 | 3.35 | 0 | 44 | X | 0.74 |
| Addison Reed | 41.0 | 3.73 | 0 | 45 | X | 0.26 |
| Hector Santiago | 39.3 | 3.66 | 0 | 32 | X | 0.32 |
| Dylan Axelrod | 38.3 | 5.63 | 6 | 4 | X | -1.46 |
| Jesse Crain | 31.7 | 1.99 | 0 | 34 | X | 1.49 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.40 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.50 |
| Francisco Liriano | 14.3 | 5.65 | 3 | 0 | X | -0.55 |
| Brett Myers | 11.0 | 0.82 | 0 | 12 | X | 0.82 |
| Leyson Septimo | 9.0 | 6.00 | 0 | 12 | X | -0.42 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Donnie Veal | 1.7 | 0.00 | 0 | 2 | X | 0.16 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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