| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 478 | 61 | 74 | 0.308 | 0.351 | 3.03 | 1B |
| Dustin Pedroia | 429 | 57 | 42 | 0.275 | 0.331 | 0.39 | 2B |
| Mike Aviles | 428 | 45 | 53 | 0.254 | 0.280 | 0.31 | SS |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.39 | DH |
| Cody Ross | 337 | 51 | 60 | 0.278 | 0.344 | 3.80 | RF-LF-DH |
| Jarrod Saltalamacchia | 320 | 42 | 46 | 0.231 | 0.287 | 1.78 | CR-DH |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.57 | 3B |
| Daniel Nava | 242 | 32 | 27 | 0.251 | 0.372 | 0.55 | LF |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.12 | RF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.25 | 3B-1B |
| Kelly Shoppach | 154 | 16 | 16 | 0.250 | 0.325 | -0.23 | CR |
| Jacoby Ellsbury | 146 | 20 | 8 | 0.246 | 0.301 | -0.46 | CF |
| Nick Punto | 131 | 10 | 9 | 0.200 | 0.298 | -1.06 | 2B |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Carl Crawford | 91 | 17 | 13 | 0.267 | 0.297 | 1.03 | LF |
| Pedro Ciriaco | 87 | 10 | 11 | 0.341 | 0.345 | 0.18 | 3B-2B-SS-DH |
| Ryan Kalish | 85 | 11 | 5 | 0.203 | 0.247 | -0.30 | CF |
| Scott Podsednik | 73 | 9 | 8 | 0.379 | 0.384 | 0.08 | LF-CF |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.09 | 1B |
| Ryan Lavarnway | 18 | 0 | 0 | 0.125 | 0.222 | -0.42 | CR-DH |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 141.0 | 5.30 | 23 | 0 | X | -4.23 |
| Clay Buchholz | 131.7 | 4.24 | 20 | 0 | X | -0.70 |
| Felix Doubront | 122.7 | 4.70 | 22 | 0 | X | -1.96 |
| Josh Beckett | 116.0 | 4.97 | 19 | 0 | X | -2.58 |
| Franklin Morales | 63.0 | 3.00 | 6 | 28 | X | 1.49 |
| Alfredo Aceves | 57.7 | 4.21 | 0 | 53 | X | -0.27 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.57 |
| Aaron Cook | 51.7 | 4.70 | 9 | 0 | X | -0.83 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.20 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.58 |
| Vicente Padilla | 39.0 | 4.62 | 0 | 41 | X | -0.55 |
| Andrew Miller | 29.3 | 3.07 | 0 | 37 | X | 0.65 |
| Mark Melancon | 26.7 | 7.42 | 0 | 26 | X | -2.12 |
| Clayton Mortensen | 26.0 | 1.73 | 0 | 11 | X | 1.38 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.42 |
| Junichi Tazawa | 20.7 | 1.74 | 0 | 15 | X | 1.09 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.44 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Craig Breslow | 4.7 | 1.93 | 0 | 6 | X | 0.23 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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