| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 443 | 55 | 62 | 0.302 | 0.345 | 1.94 | 1B |
| Mike Aviles | 399 | 41 | 52 | 0.252 | 0.273 | 0.45 | SS |
| Dustin Pedroia | 394 | 49 | 39 | 0.263 | 0.317 | 0.04 | 2B |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.38 | DH |
| Cody Ross | 302 | 47 | 53 | 0.262 | 0.334 | 3.45 | RF-LF-DH |
| Jarrod Saltalamacchia | 299 | 41 | 46 | 0.233 | 0.288 | 2.15 | CR-DH |
| Will Middlebrooks | 258 | 32 | 48 | 0.296 | 0.326 | 2.38 | 3B |
| Daniel Nava | 242 | 32 | 27 | 0.251 | 0.372 | 0.54 | LF |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.12 | RF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.24 | 3B-1B |
| Kelly Shoppach | 138 | 16 | 15 | 0.258 | 0.341 | 0.03 | CR |
| Nick Punto | 126 | 10 | 9 | 0.210 | 0.310 | -0.95 | 2B |
| Jacoby Ellsbury | 113 | 15 | 6 | 0.262 | 0.327 | -0.43 | CF |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.80 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Pedro Ciriaco | 78 | 9 | 10 | 0.329 | 0.333 | 0.17 | 3B-2B-SS-DH |
| Ryan Kalish | 70 | 7 | 5 | 0.212 | 0.243 | -0.37 | CF |
| Scott Podsednik | 70 | 9 | 8 | 0.381 | 0.386 | 0.15 | LF-CF |
| Carl Crawford | 58 | 10 | 5 | 0.222 | 0.276 | 0.22 | LF |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.09 | 1B |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Ryan Lavarnway | 4 | 0 | 0 | 0.000 | 0.250 | -0.09 | CR-DH |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 134.3 | 5.29 | 22 | 0 | X | -4.00 |
| Clay Buchholz | 115.7 | 4.75 | 18 | 0 | X | -1.97 |
| Felix Doubront | 113.3 | 4.37 | 20 | 0 | X | -0.92 |
| Josh Beckett | 111.0 | 4.54 | 18 | 0 | X | -1.35 |
| Franklin Morales | 57.0 | 3.16 | 5 | 28 | X | 1.14 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.56 |
| Alfredo Aceves | 54.0 | 3.83 | 0 | 50 | X | 0.23 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.21 |
| Aaron Cook | 44.7 | 5.24 | 8 | 0 | X | -1.27 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.59 |
| Vicente Padilla | 37.7 | 3.82 | 0 | 39 | X | 0.17 |
| Andrew Miller | 26.7 | 3.04 | 0 | 34 | X | 0.61 |
| Clayton Mortensen | 23.0 | 1.17 | 0 | 10 | X | 1.53 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.41 |
| Mark Melancon | 22.7 | 8.34 | 0 | 23 | X | -2.28 |
| Junichi Tazawa | 16.7 | 1.08 | 0 | 11 | X | 1.14 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.44 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Craig Breslow | 1.3 | 0.00 | 0 | 1 | X | 0.13 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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