| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 442 | 64 | 74 | 0.213 | 0.351 | 4.12 | DH-1B |
| Alejandro de Aza | 441 | 65 | 41 | 0.282 | 0.345 | 0.78 | CF-LF |
| Alex Rios | 413 | 63 | 64 | 0.313 | 0.346 | 3.64 | RF |
| Alexei Ramirez | 405 | 41 | 48 | 0.267 | 0.286 | -0.16 | SS |
| Gordon Beckham | 397 | 45 | 38 | 0.231 | 0.280 | -0.60 | 2B |
| Paul Konerko | 397 | 53 | 52 | 0.327 | 0.401 | 1.71 | 1B-DH |
| Dayan Viciedo | 351 | 40 | 51 | 0.255 | 0.296 | 1.32 | LF-DH |
| A.J. Pierzynski | 329 | 44 | 55 | 0.289 | 0.340 | 2.67 | CR |
| Kevin Youkilis | 132 | 21 | 22 | 0.245 | 0.364 | 1.42 | 3B-1B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.94 | 3B |
| Orlando Hudson | 113 | 7 | 11 | 0.178 | 0.239 | -0.76 | 2B |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.81 | X |
| Tyler Flowers | 96 | 10 | 2 | 0.182 | 0.250 | -0.99 | CR |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.80 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.57 | LF |
| Jordan Danks | 36 | 3 | 2 | 0.314 | 0.306 | -0.32 | LF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 140.0 | 3.15 | 20 | 0 | X | 2.79 |
| Chris Sale | 124.0 | 2.61 | 18 | 1 | X | 4.03 |
| Gavin Floyd | 115.7 | 4.28 | 19 | 0 | X | -0.74 |
| Jose Quintana | 83.7 | 2.80 | 12 | 2 | X | 2.36 |
| Philip Humber | 82.3 | 5.90 | 15 | 0 | X | -3.65 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.12 |
| Matt Thornton | 45.0 | 3.60 | 0 | 50 | X | 0.43 |
| Nate Jones | 42.0 | 3.43 | 0 | 38 | X | 0.57 |
| Hector Santiago | 39.3 | 3.66 | 0 | 32 | X | 0.32 |
| Dylan Axelrod | 38.3 | 5.63 | 6 | 4 | X | -1.46 |
| Addison Reed | 37.0 | 3.89 | 0 | 41 | X | 0.10 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.40 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.50 |
| Jesse Crain | 26.0 | 2.42 | 0 | 28 | X | 0.96 |
| Leyson Septimo | 8.3 | 4.32 | 0 | 9 | X | -0.06 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Francisco Liriano | 6.0 | 3.00 | 1 | 0 | X | 0.14 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Brett Myers | 3.7 | 0.00 | 0 | 5 | X | 0.34 |
| Donnie Veal | 1.7 | 0.00 | 0 | 2 | X | 0.16 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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