| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Alejandro de Aza | 432 | 64 | 39 | 0.278 | 0.343 | 0.71 | CF-LF |
| Adam Dunn | 429 | 64 | 74 | 0.215 | 0.357 | 4.46 | DH-1B |
| Alex Rios | 400 | 60 | 64 | 0.310 | 0.345 | 3.67 | RF |
| Alexei Ramirez | 393 | 39 | 47 | 0.269 | 0.288 | -0.16 | SS |
| Gordon Beckham | 385 | 45 | 38 | 0.230 | 0.281 | -0.29 | 2B |
| Paul Konerko | 384 | 52 | 51 | 0.334 | 0.406 | 1.84 | 1B-DH |
| Dayan Viciedo | 340 | 40 | 50 | 0.260 | 0.303 | 1.50 | LF-DH |
| A.J. Pierzynski | 320 | 41 | 50 | 0.287 | 0.338 | 2.07 | CR |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.93 | 3B |
| Kevin Youkilis | 119 | 21 | 22 | 0.273 | 0.387 | 1.73 | 3B-1B |
| Orlando Hudson | 113 | 7 | 11 | 0.178 | 0.239 | -0.75 | 2B |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.80 | X |
| Tyler Flowers | 93 | 10 | 2 | 0.176 | 0.247 | -0.91 | CR |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.80 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.56 | LF |
| Jordan Danks | 33 | 3 | 2 | 0.281 | 0.273 | -0.25 | LF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 140.0 | 3.15 | 20 | 0 | X | 2.72 |
| Chris Sale | 124.0 | 2.61 | 18 | 1 | X | 3.97 |
| Gavin Floyd | 109.0 | 4.46 | 18 | 0 | X | -1.21 |
| Philip Humber | 82.3 | 5.90 | 15 | 0 | X | -3.69 |
| Jose Quintana | 76.7 | 2.58 | 11 | 2 | X | 2.51 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.15 |
| Matt Thornton | 43.0 | 3.77 | 0 | 48 | X | 0.22 |
| Nate Jones | 42.0 | 3.43 | 0 | 38 | X | 0.54 |
| Hector Santiago | 38.3 | 3.76 | 0 | 31 | X | 0.20 |
| Dylan Axelrod | 38.3 | 5.63 | 6 | 4 | X | -1.48 |
| Addison Reed | 36.0 | 3.75 | 0 | 40 | X | 0.20 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.41 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.51 |
| Jesse Crain | 25.0 | 2.52 | 0 | 27 | X | 0.85 |
| Leyson Septimo | 8.0 | 4.50 | 0 | 8 | X | -0.10 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Brett Myers | 3.3 | 0.00 | 0 | 4 | X | 0.31 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.15 |
| Donnie Veal | 1.7 | 0.00 | 0 | 2 | X | 0.15 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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