| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 424 | 52 | 62 | 0.294 | 0.335 | 2.18 | 1B |
| Mike Aviles | 399 | 41 | 52 | 0.252 | 0.273 | 0.55 | SS |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.48 | DH |
| Dustin Pedroia | 375 | 47 | 36 | 0.271 | 0.325 | 0.06 | 2B |
| Cody Ross | 287 | 46 | 52 | 0.260 | 0.331 | 3.66 | RF-LF-DH |
| Jarrod Saltalamacchia | 284 | 38 | 46 | 0.233 | 0.285 | 2.26 | CR-DH |
| Daniel Nava | 242 | 32 | 27 | 0.251 | 0.372 | 0.61 | LF |
| Will Middlebrooks | 241 | 30 | 45 | 0.301 | 0.332 | 2.31 | 3B |
| Ryan Sweeney | 211 | 22 | 14 | 0.265 | 0.308 | -1.09 | RF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.28 | 3B-1B |
| Kelly Shoppach | 132 | 14 | 15 | 0.261 | 0.341 | 0.00 | CR |
| Nick Punto | 126 | 10 | 9 | 0.210 | 0.310 | -0.91 | 2B |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.77 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.02 | X |
| Jacoby Ellsbury | 92 | 13 | 4 | 0.259 | 0.315 | -0.34 | CF |
| Scott Podsednik | 70 | 9 | 8 | 0.381 | 0.386 | 0.17 | LF-CF |
| Ryan Kalish | 63 | 7 | 5 | 0.217 | 0.238 | -0.19 | CF |
| Pedro Ciriaco | 61 | 8 | 7 | 0.356 | 0.361 | 0.17 | 3B-2B-SS-DH |
| Carl Crawford | 38 | 7 | 2 | 0.222 | 0.263 | 0.07 | LF |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.09 | 1B |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.25 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 126.3 | 5.41 | 21 | 0 | X | -4.22 |
| Josh Beckett | 108.3 | 4.57 | 17 | 0 | X | -1.48 |
| Clay Buchholz | 107.7 | 4.93 | 17 | 0 | X | -2.38 |
| Felix Doubront | 107.0 | 4.54 | 19 | 0 | X | -1.39 |
| Franklin Morales | 56.7 | 3.18 | 5 | 27 | X | 1.07 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.61 |
| Alfredo Aceves | 50.7 | 3.73 | 0 | 48 | X | 0.30 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.18 |
| Aaron Cook | 40.0 | 4.50 | 7 | 0 | X | -0.48 |
| Matt Albers | 39.3 | 2.29 | 0 | 39 | X | 1.56 |
| Vicente Padilla | 36.7 | 3.93 | 0 | 38 | X | 0.05 |
| Andrew Miller | 24.3 | 2.59 | 0 | 32 | X | 0.79 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.43 |
| Mark Melancon | 22.0 | 8.59 | 0 | 22 | X | -2.36 |
| Clayton Mortensen | 20.3 | 1.33 | 0 | 9 | X | 1.26 |
| Junichi Tazawa | 15.3 | 1.17 | 0 | 10 | X | 1.01 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.43 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.41 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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