| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Alejandro de Aza | 424 | 63 | 37 | 0.279 | 0.344 | 0.60 | CF-LF |
| Adam Dunn | 416 | 59 | 72 | 0.210 | 0.353 | 4.05 | DH-1B |
| Alex Rios | 387 | 57 | 59 | 0.314 | 0.349 | 3.15 | RF |
| Alexei Ramirez | 384 | 36 | 45 | 0.265 | 0.284 | -0.46 | SS |
| Gordon Beckham | 373 | 42 | 38 | 0.229 | 0.282 | -0.31 | 2B |
| Paul Konerko | 371 | 51 | 48 | 0.336 | 0.410 | 1.74 | 1B-DH |
| Dayan Viciedo | 327 | 39 | 46 | 0.256 | 0.294 | 1.29 | LF-DH |
| A.J. Pierzynski | 320 | 41 | 50 | 0.287 | 0.338 | 2.09 | CR |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.92 | 3B |
| Orlando Hudson | 113 | 7 | 11 | 0.178 | 0.239 | -0.75 | 2B |
| Kevin Youkilis | 108 | 18 | 19 | 0.272 | 0.370 | 1.36 | 3B-1B |
| Eduardo Escobar | 90 | 11 | 2 | 0.200 | 0.278 | -0.74 | X |
| Tyler Flowers | 81 | 9 | 2 | 0.178 | 0.259 | -0.74 | CR |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.79 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.56 | LF |
| Jordan Danks | 28 | 2 | 2 | 0.296 | 0.286 | -0.23 | LF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 134.0 | 3.22 | 19 | 0 | X | 2.34 |
| Chris Sale | 117.7 | 2.37 | 17 | 1 | X | 4.40 |
| Gavin Floyd | 109.0 | 4.46 | 18 | 0 | X | -1.23 |
| Jose Quintana | 76.7 | 2.58 | 11 | 2 | X | 2.49 |
| Philip Humber | 76.3 | 6.25 | 14 | 0 | X | -4.05 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.16 |
| Nate Jones | 42.0 | 3.43 | 0 | 37 | X | 0.53 |
| Matt Thornton | 41.3 | 3.70 | 0 | 46 | X | 0.26 |
| Dylan Axelrod | 38.3 | 5.63 | 6 | 4 | X | -1.49 |
| Hector Santiago | 38.0 | 3.79 | 0 | 30 | X | 0.16 |
| Addison Reed | 35.0 | 3.86 | 0 | 39 | X | 0.10 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.42 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.52 |
| Jesse Crain | 23.3 | 2.70 | 0 | 25 | X | 0.69 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Leyson Septimo | 6.0 | 6.00 | 0 | 7 | X | -0.28 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Donnie Veal | 1.7 | 0.00 | 0 | 2 | X | 0.15 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.15 |
| Brett Myers | 1.3 | 0.00 | 0 | 2 | X | 0.12 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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