| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 411 | 50 | 58 | 0.293 | 0.333 | 1.88 | 1B |
| Mike Aviles | 388 | 41 | 52 | 0.260 | 0.281 | 0.84 | SS |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.51 | DH |
| Dustin Pedroia | 362 | 43 | 33 | 0.267 | 0.323 | -0.35 | 2B |
| Jarrod Saltalamacchia | 280 | 37 | 45 | 0.233 | 0.286 | 2.17 | CR-DH |
| Cody Ross | 274 | 46 | 52 | 0.266 | 0.339 | 3.99 | RF-LF-DH |
| Daniel Nava | 235 | 32 | 27 | 0.250 | 0.374 | 0.79 | LF |
| Will Middlebrooks | 229 | 29 | 42 | 0.293 | 0.323 | 2.19 | 3B |
| Ryan Sweeney | 210 | 22 | 14 | 0.267 | 0.310 | -1.05 | RF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.30 | 3B-1B |
| Nick Punto | 126 | 10 | 9 | 0.210 | 0.310 | -0.90 | 2B |
| Kelly Shoppach | 125 | 14 | 15 | 0.278 | 0.360 | 0.17 | CR |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.76 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.03 | X |
| Jacoby Ellsbury | 79 | 11 | 4 | 0.293 | 0.329 | -0.24 | CF |
| Scott Podsednik | 70 | 9 | 8 | 0.381 | 0.386 | 0.17 | LF-CF |
| Ryan Kalish | 63 | 7 | 5 | 0.217 | 0.238 | -0.19 | CF |
| Pedro Ciriaco | 52 | 5 | 6 | 0.320 | 0.327 | -0.04 | 3B-2B-SS-DH |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.08 | 1B |
| Carl Crawford | 31 | 6 | 1 | 0.241 | 0.290 | 0.02 | LF |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.25 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 120.3 | 5.39 | 20 | 0 | X | -3.99 |
| Clay Buchholz | 107.7 | 4.93 | 17 | 0 | X | -2.43 |
| Felix Doubront | 107.0 | 4.54 | 19 | 0 | X | -1.44 |
| Josh Beckett | 101.3 | 4.53 | 16 | 0 | X | -1.34 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.63 |
| Franklin Morales | 54.7 | 3.29 | 5 | 26 | X | 0.86 |
| Alfredo Aceves | 49.7 | 3.81 | 0 | 47 | X | 0.18 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.16 |
| Matt Albers | 37.3 | 2.17 | 0 | 37 | X | 1.56 |
| Aaron Cook | 36.0 | 3.50 | 6 | 0 | X | 0.39 |
| Vicente Padilla | 36.0 | 3.50 | 0 | 37 | X | 0.39 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.44 |
| Andrew Miller | 23.0 | 2.74 | 0 | 30 | X | 0.66 |
| Mark Melancon | 21.0 | 7.29 | 0 | 21 | X | -1.63 |
| Clayton Mortensen | 20.3 | 1.33 | 0 | 9 | X | 1.25 |
| Junichi Tazawa | 15.3 | 1.17 | 0 | 10 | X | 1.00 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.42 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.52 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.41 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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