| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 403 | 50 | 58 | 0.296 | 0.337 | 2.06 | 1B |
| Mike Aviles | 381 | 41 | 51 | 0.262 | 0.283 | 0.88 | SS |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.50 | DH |
| Dustin Pedroia | 354 | 43 | 33 | 0.265 | 0.322 | -0.18 | 2B |
| Jarrod Saltalamacchia | 275 | 36 | 44 | 0.228 | 0.280 | 2.06 | CR-DH |
| Cody Ross | 266 | 45 | 52 | 0.269 | 0.342 | 4.06 | RF-LF-DH |
| Daniel Nava | 234 | 31 | 27 | 0.250 | 0.372 | 0.70 | LF |
| Will Middlebrooks | 221 | 29 | 42 | 0.285 | 0.317 | 2.36 | 3B |
| Ryan Sweeney | 206 | 22 | 14 | 0.272 | 0.316 | -0.97 | RF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.29 | 3B-1B |
| Nick Punto | 126 | 10 | 9 | 0.210 | 0.310 | -0.91 | 2B |
| Kelly Shoppach | 122 | 14 | 14 | 0.274 | 0.352 | 0.13 | CR |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.76 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.03 | X |
| Jacoby Ellsbury | 70 | 11 | 4 | 0.288 | 0.329 | -0.04 | CF |
| Scott Podsednik | 70 | 9 | 8 | 0.381 | 0.386 | 0.17 | LF-CF |
| Ryan Kalish | 63 | 7 | 5 | 0.217 | 0.238 | -0.19 | CF |
| Pedro Ciriaco | 47 | 5 | 6 | 0.356 | 0.362 | 0.07 | 3B-2B-SS-DH |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.08 | 1B |
| Carl Crawford | 24 | 6 | 1 | 0.318 | 0.375 | 0.18 | LF |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.25 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 120.3 | 5.39 | 20 | 0 | X | -3.98 |
| Felix Doubront | 102.0 | 4.24 | 18 | 0 | X | -0.64 |
| Josh Beckett | 101.3 | 4.53 | 16 | 0 | X | -1.33 |
| Clay Buchholz | 100.7 | 5.19 | 16 | 0 | X | -2.86 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.63 |
| Franklin Morales | 52.7 | 3.08 | 5 | 25 | X | 1.09 |
| Alfredo Aceves | 48.7 | 3.88 | 0 | 46 | X | 0.09 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.16 |
| Matt Albers | 37.3 | 2.17 | 0 | 37 | X | 1.57 |
| Aaron Cook | 36.0 | 3.50 | 6 | 0 | X | 0.39 |
| Vicente Padilla | 35.0 | 3.60 | 0 | 36 | X | 0.30 |
| Andrew Miller | 23.0 | 2.74 | 0 | 30 | X | 0.66 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.44 |
| Clayton Mortensen | 20.3 | 1.33 | 0 | 9 | X | 1.25 |
| Mark Melancon | 20.0 | 7.65 | 0 | 20 | X | -1.72 |
| Junichi Tazawa | 15.3 | 1.17 | 0 | 10 | X | 1.00 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.42 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.52 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.41 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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