| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| David Ortiz | 375 | 67 | 58 | 0.315 | 0.413 | 4.54 | DH |
| Adrian Gonzalez | 375 | 44 | 46 | 0.286 | 0.331 | 0.87 | 1B |
| Mike Aviles | 358 | 40 | 47 | 0.266 | 0.288 | 0.94 | SS |
| Dustin Pedroia | 338 | 41 | 33 | 0.266 | 0.325 | 0.03 | 2B |
| Jarrod Saltalamacchia | 259 | 35 | 41 | 0.235 | 0.290 | 2.05 | CR-DH |
| Cody Ross | 240 | 39 | 43 | 0.258 | 0.338 | 3.12 | RF-LF-DH |
| Daniel Nava | 220 | 31 | 27 | 0.265 | 0.382 | 1.05 | LF |
| Will Middlebrooks | 197 | 27 | 41 | 0.301 | 0.335 | 2.63 | 3B |
| Ryan Sweeney | 196 | 21 | 14 | 0.279 | 0.316 | -0.81 | RF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.32 | 3B-1B |
| Nick Punto | 120 | 10 | 8 | 0.212 | 0.317 | -0.86 | 2B |
| Kelly Shoppach | 111 | 13 | 12 | 0.263 | 0.351 | 0.08 | CR |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.75 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.04 | X |
| Scott Podsednik | 70 | 9 | 8 | 0.381 | 0.386 | 0.18 | LF-CF |
| Ryan Kalish | 63 | 7 | 5 | 0.217 | 0.238 | -0.18 | CF |
| Jacoby Ellsbury | 44 | 5 | 3 | 0.275 | 0.341 | -0.17 | CF |
| Mauro Gomez | 27 | 3 | 3 | 0.308 | 0.333 | 0.01 | 1B |
| Pedro Ciriaco | 26 | 4 | 6 | 0.417 | 0.423 | 0.45 | 3B-2B-SS-DH |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.25 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 112.3 | 4.41 | 18 | 0 | X | -1.18 |
| Felix Doubront | 96.0 | 4.41 | 17 | 0 | X | -1.01 |
| Josh Beckett | 95.3 | 4.44 | 15 | 0 | X | -1.07 |
| Clay Buchholz | 92.7 | 5.54 | 15 | 0 | X | -3.42 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.65 |
| Franklin Morales | 51.3 | 3.16 | 5 | 23 | X | 0.96 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.14 |
| Alfredo Aceves | 45.7 | 4.14 | 0 | 43 | X | -0.20 |
| Matt Albers | 35.7 | 2.27 | 0 | 34 | X | 1.40 |
| Vicente Padilla | 33.0 | 3.82 | 0 | 34 | X | 0.10 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.45 |
| Aaron Cook | 22.7 | 4.37 | 4 | 0 | X | -0.22 |
| Andrew Miller | 20.7 | 3.05 | 0 | 27 | X | 0.44 |
| Clayton Mortensen | 20.3 | 1.33 | 0 | 9 | X | 1.25 |
| Mark Melancon | 17.3 | 6.23 | 0 | 17 | X | -0.92 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.42 |
| Junichi Tazawa | 6.7 | 0.00 | 0 | 6 | X | 0.62 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.52 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.41 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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