| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 371 | 43 | 45 | 0.283 | 0.329 | 0.72 | 1B |
| David Ortiz | 370 | 67 | 58 | 0.313 | 0.411 | 4.63 | DH |
| Mike Aviles | 354 | 39 | 45 | 0.263 | 0.285 | 0.69 | SS |
| Dustin Pedroia | 338 | 41 | 33 | 0.266 | 0.325 | 0.01 | 2B |
| Jarrod Saltalamacchia | 254 | 35 | 41 | 0.239 | 0.291 | 2.15 | CR-DH |
| Cody Ross | 235 | 38 | 42 | 0.259 | 0.340 | 3.00 | RF-LF-DH |
| Daniel Nava | 215 | 29 | 26 | 0.264 | 0.377 | 0.84 | LF |
| Ryan Sweeney | 196 | 21 | 14 | 0.279 | 0.316 | -0.83 | RF-CF |
| Will Middlebrooks | 193 | 26 | 39 | 0.291 | 0.326 | 2.39 | 3B |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.31 | 3B-1B |
| Nick Punto | 120 | 10 | 8 | 0.212 | 0.317 | -0.87 | 2B |
| Kelly Shoppach | 111 | 13 | 12 | 0.263 | 0.351 | 0.08 | CR |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.75 | CF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.04 | X |
| Scott Podsednik | 70 | 9 | 8 | 0.381 | 0.386 | 0.18 | LF-CF |
| Ryan Kalish | 63 | 7 | 5 | 0.217 | 0.238 | -0.19 | CF |
| Jacoby Ellsbury | 39 | 4 | 3 | 0.229 | 0.308 | -0.16 | CF |
| Mauro Gomez | 27 | 3 | 3 | 0.308 | 0.333 | 0.01 | 1B |
| Pedro Ciriaco | 22 | 4 | 6 | 0.500 | 0.500 | 0.54 | 3B-2B-SS-DH |
| Brent Lillibridge | 15 | 0 | 0 | 0.133 | 0.133 | -0.34 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.25 | X |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 112.3 | 4.41 | 18 | 0 | X | -1.16 |
| Felix Doubront | 96.0 | 4.41 | 17 | 0 | X | -0.99 |
| Clay Buchholz | 92.7 | 5.54 | 15 | 0 | X | -3.40 |
| Josh Beckett | 89.3 | 4.43 | 14 | 0 | X | -0.98 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.63 |
| Franklin Morales | 51.3 | 3.16 | 5 | 23 | X | 0.97 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.16 |
| Alfredo Aceves | 44.7 | 4.23 | 0 | 42 | X | -0.28 |
| Matt Albers | 35.7 | 2.27 | 0 | 34 | X | 1.41 |
| Vicente Padilla | 33.0 | 3.82 | 0 | 34 | X | 0.11 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.44 |
| Aaron Cook | 22.7 | 4.37 | 4 | 0 | X | -0.21 |
| Andrew Miller | 20.7 | 3.05 | 0 | 27 | X | 0.44 |
| Clayton Mortensen | 20.3 | 1.33 | 0 | 9 | X | 1.25 |
| Mark Melancon | 15.7 | 6.89 | 0 | 16 | X | -1.07 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.42 |
| Junichi Tazawa | 6.3 | 0.00 | 0 | 5 | X | 0.59 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.52 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.41 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
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