| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 711 | 79 | 49 | 0.278 | 0.321 | -3.00 | LF |
| Alexei Ramirez | 684 | 81 | 71 | 0.269 | 0.325 | 0.15 | SS |
| Paul Konerko | 639 | 74 | 105 | 0.300 | 0.388 | 4.02 | 1B-DH |
| Alex Rios | 570 | 63 | 44 | 0.227 | 0.265 | -1.94 | CF |
| Gordon Beckham | 557 | 60 | 44 | 0.230 | 0.293 | -1.96 | 2B |
| A.J. Pierzynski | 500 | 38 | 48 | 0.287 | 0.322 | -2.53 | CR |
| Adam Dunn | 496 | 38 | 42 | 0.159 | 0.292 | -3.07 | DH-1B |
| Carlos Quentin | 483 | 60 | 76 | 0.254 | 0.340 | 3.11 | RF-DH |
| Brent Morel | 444 | 44 | 41 | 0.244 | 0.284 | -1.34 | 3B |
| Brent Lillibridge | 216 | 29 | 29 | 0.258 | 0.333 | 1.10 | RF-1B-CF |
| Omar Vizquel | 182 | 16 | 8 | 0.249 | 0.280 | -1.69 | 3B-2B |
| Alejandro de Aza | 171 | 29 | 23 | 0.329 | 0.398 | 1.51 | RF-CF |
| Mark Teahen | 130 | 10 | 11 | 0.203 | 0.277 | -0.80 | X |
| Tyler Flowers | 129 | 13 | 16 | 0.209 | 0.310 | 0.06 | CR |
| Dayan Viciedo | 113 | 11 | 6 | 0.255 | 0.327 | -0.83 | RF |
| Ramon Castro | 75 | 6 | 10 | 0.235 | 0.307 | -0.05 | CR |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | -0.24 | X |
| Donny Lucy | 11 | 1 | 1 | 0.200 | 0.273 | -0.04 | X |
| Eduardo Escobar | 7 | 0 | 0 | 0.286 | 0.286 | -0.16 | X |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 205.3 | 3.55 | 31 | 0 | X | 1.73 |
| Gavin Floyd | 193.7 | 4.37 | 30 | 1 | X | -2.06 |
| John Danks | 170.3 | 4.33 | 27 | 0 | X | -1.67 |
| Philip Humber | 163.0 | 3.75 | 26 | 2 | X | 0.60 |
| Edwin Jackson | 121.7 | 3.92 | 19 | 0 | X | -0.02 |
| Jake Peavy | 111.7 | 4.92 | 18 | 1 | X | -2.62 |
| Chris Sale | 71.0 | 2.79 | 0 | 58 | X | 1.86 |
| Jesse Crain | 65.3 | 2.76 | 0 | 67 | X | 1.76 |
| Sergio Santos | 63.3 | 3.55 | 0 | 63 | X | 0.53 |
| Matt Thornton | 59.7 | 3.17 | 0 | 62 | X | 1.04 |
| Will Ohman | 53.3 | 4.22 | 0 | 59 | X | -0.38 |
| Zach Stewart | 50.7 | 6.22 | 8 | 2 | X | -2.73 |
| Tony Pena | 20.3 | 6.20 | 0 | 17 | X | -1.08 |
| Brian Bruney | 19.7 | 6.86 | 0 | 23 | X | -1.35 |
| Dylan Axelrod | 18.7 | 2.89 | 3 | 1 | X | 0.44 |
| Jason Frasor | 17.7 | 5.60 | 0 | 20 | X | -0.70 |
| Josh Kinney | 17.7 | 6.62 | 0 | 13 | X | -1.12 |
| Jeff Gray | 13.3 | 2.70 | 0 | 6 | X | 0.38 |
| Addison Reed | 7.3 | 3.68 | 0 | 6 | X | 0.04 |
| Shane Lindsay | 6.0 | 12.00 | 0 | 4 | X | -1.13 |
| Hector Santiago | 5.3 | 0.00 | 0 | 2 | X | 0.49 |
| Lucas Harrell | 5.0 | 7.20 | 0 | 3 | X | -0.38 |
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