| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Jacoby Ellsbury | 732 | 119 | 105 | 0.319 | 0.373 | 7.27 | CF |
| Dustin Pedroia | 731 | 103 | 91 | 0.307 | 0.386 | 4.14 | 2B |
| Adrian Gonzalez | 715 | 111 | 118 | 0.338 | 0.410 | 8.17 | 1B |
| David Ortiz | 605 | 87 | 96 | 0.309 | 0.398 | 5.78 | DH |
| Carl Crawford | 539 | 65 | 56 | 0.254 | 0.288 | 0.74 | LF |
| Kevin Youkilis | 517 | 68 | 81 | 0.258 | 0.373 | 4.17 | 3B |
| Marco Scutaro | 445 | 60 | 54 | 0.299 | 0.353 | 2.09 | SS |
| Jarrod Saltalamacchia | 386 | 51 | 56 | 0.235 | 0.288 | 2.67 | CR |
| Jed Lowrie | 341 | 43 | 36 | 0.252 | 0.302 | 0.72 | SS-3B |
| J.D. Drew | 286 | 23 | 22 | 0.222 | 0.315 | -1.62 | RF |
| Josh Reddick | 278 | 40 | 29 | 0.280 | 0.327 | 1.07 | RF-LF |
| Jason Varitek | 250 | 33 | 36 | 0.221 | 0.296 | 1.69 | CR |
| Darnell McDonald | 175 | 23 | 24 | 0.236 | 0.303 | 1.05 | RF-LF-CF |
| Mike Aviles | 107 | 16 | 8 | 0.317 | 0.336 | 0.14 | 3B-2B |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Ryan Lavarnway | 43 | 5 | 8 | 0.231 | 0.302 | 0.41 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Conor Jackson | 22 | 2 | 5 | 0.158 | 0.227 | 0.25 | 1B-RF-LF |
| Jose Iglesias | 6 | 0 | 0 | 0.333 | 0.333 | -0.13 | X |
| Lars Anderson | 5 | 0 | 0 | 0.000 | 0.000 | -0.11 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 193.0 | 2.89 | 30 | 0 | X | 4.63 |
| Jon Lester | 191.7 | 3.47 | 31 | 0 | X | 1.99 |
| John Lackey | 160.0 | 6.41 | 28 | 0 | X | -9.31 |
| Tim Wakefield | 154.7 | 5.12 | 23 | 10 | X | -4.34 |
| Alfredo Aceves | 114.0 | 2.61 | 4 | 51 | X | 3.50 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.84 |
| Daniel Bard | 73.0 | 3.33 | 0 | 70 | X | 1.01 |
| Andrew Miller | 65.0 | 5.54 | 12 | 5 | X | -2.46 |
| Matt Albers | 64.7 | 4.59 | 0 | 56 | X | -1.02 |
| Jonathan Papelbon | 64.3 | 2.94 | 0 | 63 | X | 1.47 |
| Dan Wheeler | 49.3 | 4.56 | 0 | 47 | X | -0.74 |
| Erik Bedard | 38.0 | 4.03 | 8 | 0 | X | -0.09 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Franklin Morales | 32.3 | 3.90 | 0 | 36 | X | 0.02 |
| Scott Atchison | 30.3 | 3.26 | 0 | 17 | X | 0.46 |
| Kyle Weiland | 24.7 | 7.66 | 5 | 2 | X | -2.15 |
| Michael Bowden | 20.0 | 4.05 | 0 | 14 | X | -0.06 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Felix Doubront | 10.3 | 6.10 | 0 | 11 | X | -0.53 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Junichi Tazawa | 3.0 | 6.00 | 0 | 3 | X | -0.15 |
| Trever Miller | 2.0 | 0.00 | 0 | 3 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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