| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Jacoby Ellsbury | 722 | 118 | 103 | 0.321 | 0.375 | 7.17 | CF |
| Dustin Pedroia | 721 | 102 | 89 | 0.303 | 0.381 | 4.04 | 2B |
| Adrian Gonzalez | 706 | 110 | 118 | 0.338 | 0.407 | 8.26 | 1B |
| David Ortiz | 595 | 86 | 96 | 0.308 | 0.397 | 5.90 | DH |
| Carl Crawford | 531 | 64 | 56 | 0.255 | 0.288 | 0.81 | LF |
| Kevin Youkilis | 517 | 68 | 81 | 0.258 | 0.373 | 4.16 | 3B |
| Marco Scutaro | 437 | 57 | 52 | 0.295 | 0.350 | 1.74 | SS |
| Jarrod Saltalamacchia | 386 | 51 | 56 | 0.235 | 0.288 | 2.66 | CR |
| Jed Lowrie | 336 | 43 | 36 | 0.257 | 0.307 | 0.83 | SS-3B |
| J.D. Drew | 280 | 23 | 22 | 0.223 | 0.318 | -1.49 | RF |
| Josh Reddick | 278 | 40 | 29 | 0.280 | 0.327 | 1.07 | RF-LF |
| Jason Varitek | 250 | 33 | 36 | 0.221 | 0.296 | 1.69 | CR |
| Darnell McDonald | 173 | 23 | 24 | 0.232 | 0.301 | 1.09 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Mike Aviles | 103 | 15 | 8 | 0.327 | 0.340 | 0.13 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 34 | 3 | 4 | 0.233 | 0.324 | -0.02 | X |
| Conor Jackson | 22 | 2 | 5 | 0.158 | 0.227 | 0.25 | 1B-RF-LF |
| Jose Iglesias | 6 | 0 | 0 | 0.333 | 0.333 | -0.13 | X |
| Lars Anderson | 5 | 0 | 0 | 0.000 | 0.000 | -0.11 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 193.0 | 2.89 | 30 | 0 | X | 4.62 |
| Jon Lester | 185.7 | 3.49 | 30 | 0 | X | 1.85 |
| John Lackey | 160.0 | 6.41 | 28 | 0 | X | -9.32 |
| Tim Wakefield | 154.7 | 5.12 | 23 | 10 | X | -4.35 |
| Alfredo Aceves | 109.3 | 2.63 | 4 | 49 | X | 3.27 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.83 |
| Daniel Bard | 71.0 | 3.17 | 0 | 68 | X | 1.24 |
| Andrew Miller | 65.0 | 5.54 | 12 | 5 | X | -2.46 |
| Matt Albers | 64.7 | 4.59 | 0 | 56 | X | -1.02 |
| Jonathan Papelbon | 62.7 | 2.59 | 0 | 61 | X | 1.95 |
| Dan Wheeler | 49.3 | 4.56 | 0 | 47 | X | -0.74 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Erik Bedard | 34.7 | 3.63 | 7 | 0 | X | 0.23 |
| Franklin Morales | 32.3 | 3.90 | 0 | 36 | X | 0.01 |
| Scott Atchison | 30.3 | 3.26 | 0 | 17 | X | 0.46 |
| Kyle Weiland | 24.7 | 7.66 | 5 | 2 | X | -2.16 |
| Michael Bowden | 20.0 | 4.05 | 0 | 14 | X | -0.06 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Felix Doubront | 10.3 | 6.10 | 0 | 11 | X | -0.53 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Junichi Tazawa | 3.0 | 6.00 | 0 | 3 | X | -0.15 |
| Trever Miller | 2.0 | 0.00 | 0 | 3 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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