| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 690 | 79 | 48 | 0.282 | 0.325 | -2.56 | LF |
| Alexei Ramirez | 664 | 80 | 69 | 0.268 | 0.324 | 0.35 | SS |
| Paul Konerko | 631 | 74 | 104 | 0.302 | 0.388 | 4.15 | 1B-DH |
| Alex Rios | 565 | 61 | 42 | 0.224 | 0.262 | -2.20 | CF |
| Gordon Beckham | 539 | 58 | 43 | 0.227 | 0.289 | -1.81 | 2B |
| Carlos Quentin | 483 | 60 | 76 | 0.254 | 0.340 | 3.15 | RF-DH |
| A.J. Pierzynski | 481 | 37 | 47 | 0.287 | 0.322 | -2.26 | CR |
| Adam Dunn | 481 | 37 | 42 | 0.163 | 0.293 | -2.79 | DH-1B |
| Brent Morel | 425 | 42 | 39 | 0.253 | 0.292 | -1.29 | 3B |
| Brent Lillibridge | 216 | 29 | 29 | 0.258 | 0.333 | 1.11 | RF-1B-CF |
| Omar Vizquel | 182 | 16 | 8 | 0.249 | 0.280 | -1.67 | 3B-2B |
| Alejandro de Aza | 154 | 26 | 23 | 0.319 | 0.383 | 1.60 | RF-CF |
| Mark Teahen | 130 | 10 | 11 | 0.203 | 0.277 | -0.79 | X |
| Tyler Flowers | 118 | 11 | 12 | 0.208 | 0.305 | -0.30 | CR |
| Dayan Viciedo | 96 | 10 | 5 | 0.271 | 0.354 | -0.64 | RF |
| Ramon Castro | 75 | 6 | 10 | 0.235 | 0.307 | -0.05 | CR |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | -0.24 | X |
| Donny Lucy | 7 | 1 | 1 | 0.286 | 0.286 | 0.05 | X |
| Eduardo Escobar | 7 | 0 | 0 | 0.286 | 0.286 | -0.16 | X |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 198.3 | 3.68 | 30 | 0 | X | 1.06 |
| Gavin Floyd | 185.7 | 4.46 | 29 | 1 | X | -2.40 |
| John Danks | 163.0 | 4.36 | 26 | 0 | X | -1.74 |
| Philip Humber | 156.3 | 3.86 | 25 | 2 | X | 0.18 |
| Edwin Jackson | 121.7 | 3.92 | 19 | 0 | X | -0.04 |
| Jake Peavy | 111.7 | 4.92 | 18 | 1 | X | -2.63 |
| Chris Sale | 68.3 | 2.63 | 0 | 55 | X | 2.03 |
| Jesse Crain | 64.3 | 2.52 | 0 | 64 | X | 2.08 |
| Sergio Santos | 61.3 | 3.38 | 0 | 60 | X | 0.76 |
| Matt Thornton | 56.7 | 3.34 | 0 | 59 | X | 0.75 |
| Will Ohman | 52.0 | 4.33 | 0 | 57 | X | -0.51 |
| Zach Stewart | 50.7 | 6.22 | 8 | 2 | X | -2.73 |
| Tony Pena | 20.3 | 6.20 | 0 | 17 | X | -1.09 |
| Brian Bruney | 19.7 | 6.86 | 0 | 23 | X | -1.36 |
| Jason Frasor | 17.7 | 5.60 | 0 | 20 | X | -0.70 |
| Josh Kinney | 17.7 | 6.62 | 0 | 13 | X | -1.12 |
| Jeff Gray | 13.3 | 2.70 | 0 | 6 | X | 0.38 |
| Dylan Axelrod | 12.7 | 4.26 | 2 | 1 | X | -0.11 |
| Addison Reed | 7.3 | 3.68 | 0 | 6 | X | 0.04 |
| Shane Lindsay | 6.0 | 12.00 | 0 | 4 | X | -1.13 |
| Hector Santiago | 5.3 | 0.00 | 0 | 2 | X | 0.49 |
| Lucas Harrell | 5.0 | 7.20 | 0 | 3 | X | -0.38 |
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