| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 702 | 102 | 88 | 0.300 | 0.380 | 4.36 | 2B |
| Jacoby Ellsbury | 701 | 114 | 98 | 0.317 | 0.371 | 6.69 | CF |
| Adrian Gonzalez | 689 | 110 | 117 | 0.341 | 0.409 | 8.53 | 1B |
| David Ortiz | 576 | 86 | 96 | 0.312 | 0.401 | 6.32 | DH |
| Kevin Youkilis | 517 | 68 | 81 | 0.258 | 0.373 | 4.16 | 3B |
| Carl Crawford | 511 | 63 | 55 | 0.259 | 0.294 | 1.04 | LF |
| Marco Scutaro | 420 | 54 | 51 | 0.293 | 0.348 | 1.70 | SS |
| Jarrod Saltalamacchia | 373 | 51 | 56 | 0.241 | 0.295 | 2.95 | CR |
| Jed Lowrie | 328 | 40 | 35 | 0.253 | 0.302 | 0.59 | SS-3B |
| Josh Reddick | 276 | 40 | 29 | 0.282 | 0.330 | 1.12 | RF-LF |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.40 | RF |
| Jason Varitek | 247 | 33 | 35 | 0.218 | 0.291 | 1.65 | CR |
| Darnell McDonald | 172 | 22 | 24 | 0.227 | 0.297 | 1.01 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Mike Aviles | 93 | 15 | 8 | 0.348 | 0.366 | 0.35 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 33 | 3 | 4 | 0.241 | 0.333 | 0.00 | X |
| Conor Jackson | 17 | 1 | 5 | 0.143 | 0.235 | 0.25 | 1B-RF-LF |
| Jose Iglesias | 6 | 0 | 0 | 0.333 | 0.333 | -0.13 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Lars Anderson | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 187.0 | 2.70 | 29 | 0 | X | 5.32 |
| Jon Lester | 183.0 | 3.15 | 29 | 0 | X | 3.28 |
| John Lackey | 154.0 | 6.49 | 27 | 0 | X | -9.24 |
| Tim Wakefield | 150.7 | 5.08 | 22 | 10 | X | -4.09 |
| Alfredo Aceves | 106.7 | 2.70 | 4 | 47 | X | 3.02 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.83 |
| Daniel Bard | 70.0 | 3.21 | 0 | 67 | X | 1.14 |
| Andrew Miller | 64.0 | 5.62 | 12 | 4 | X | -2.55 |
| Matt Albers | 63.0 | 4.57 | 0 | 55 | X | -0.96 |
| Jonathan Papelbon | 60.3 | 2.69 | 0 | 60 | X | 1.73 |
| Dan Wheeler | 49.3 | 4.56 | 0 | 47 | X | -0.74 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Erik Bedard | 34.7 | 3.63 | 7 | 0 | X | 0.23 |
| Franklin Morales | 30.3 | 4.15 | 0 | 35 | X | -0.17 |
| Scott Atchison | 26.7 | 3.71 | 0 | 15 | X | 0.13 |
| Kyle Weiland | 23.7 | 7.99 | 5 | 1 | X | -2.25 |
| Michael Bowden | 19.0 | 4.26 | 0 | 13 | X | -0.15 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Felix Doubront | 9.3 | 6.75 | 0 | 10 | X | -0.62 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Trever Miller | 1.7 | 0.00 | 0 | 2 | X | 0.15 |
| Junichi Tazawa | 1.3 | 6.75 | 0 | 2 | X | -0.09 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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