| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 668 | 78 | 46 | 0.283 | 0.326 | -2.33 | LF |
| Alexei Ramirez | 639 | 77 | 67 | 0.271 | 0.326 | 0.44 | SS |
| Paul Konerko | 614 | 71 | 101 | 0.305 | 0.391 | 3.95 | 1B-DH |
| Alex Rios | 548 | 57 | 41 | 0.222 | 0.259 | -2.30 | CF |
| Gordon Beckham | 517 | 56 | 41 | 0.230 | 0.292 | -1.70 | 2B |
| Carlos Quentin | 483 | 60 | 76 | 0.254 | 0.340 | 3.18 | RF-DH |
| A.J. Pierzynski | 461 | 33 | 43 | 0.286 | 0.323 | -2.61 | CR |
| Adam Dunn | 457 | 35 | 40 | 0.161 | 0.291 | -2.63 | DH-1B |
| Brent Morel | 405 | 39 | 34 | 0.251 | 0.286 | -1.64 | 3B |
| Brent Lillibridge | 216 | 29 | 29 | 0.258 | 0.333 | 1.13 | RF-1B-CF |
| Omar Vizquel | 178 | 16 | 8 | 0.242 | 0.275 | -1.57 | 3B-2B |
| Alejandro de Aza | 134 | 24 | 17 | 0.322 | 0.381 | 1.23 | RF-CF |
| Mark Teahen | 130 | 10 | 11 | 0.203 | 0.277 | -0.78 | X |
| Tyler Flowers | 109 | 10 | 11 | 0.207 | 0.312 | -0.30 | CR |
| Dayan Viciedo | 76 | 6 | 5 | 0.284 | 0.368 | -0.59 | RF |
| Ramon Castro | 75 | 6 | 10 | 0.235 | 0.307 | -0.04 | CR |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | -0.24 | X |
| Donny Lucy | 6 | 1 | 1 | 0.333 | 0.333 | 0.07 | X |
| Eduardo Escobar | 5 | 0 | 0 | 0.400 | 0.400 | -0.11 | X |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 192.3 | 3.70 | 29 | 0 | X | 0.89 |
| Gavin Floyd | 179.0 | 4.42 | 28 | 1 | X | -2.21 |
| John Danks | 157.0 | 4.36 | 25 | 0 | X | -1.69 |
| Philip Humber | 150.3 | 3.59 | 24 | 2 | X | 1.06 |
| Edwin Jackson | 121.7 | 3.92 | 19 | 0 | X | -0.07 |
| Jake Peavy | 111.7 | 4.92 | 18 | 1 | X | -2.66 |
| Chris Sale | 65.3 | 2.76 | 0 | 53 | X | 1.74 |
| Jesse Crain | 62.3 | 2.45 | 0 | 61 | X | 2.10 |
| Sergio Santos | 59.3 | 3.34 | 0 | 58 | X | 0.77 |
| Matt Thornton | 54.0 | 3.50 | 0 | 57 | X | 0.50 |
| Will Ohman | 48.0 | 4.69 | 0 | 54 | X | -0.89 |
| Zach Stewart | 46.7 | 5.01 | 7 | 2 | X | -1.22 |
| Tony Pena | 20.3 | 6.20 | 0 | 17 | X | -1.09 |
| Brian Bruney | 19.7 | 6.86 | 0 | 23 | X | -1.36 |
| Jason Frasor | 15.7 | 4.60 | 0 | 18 | X | -0.26 |
| Josh Kinney | 15.7 | 6.32 | 0 | 11 | X | -0.89 |
| Jeff Gray | 13.3 | 2.70 | 0 | 6 | X | 0.37 |
| Dylan Axelrod | 8.0 | 2.25 | 1 | 1 | X | 0.31 |
| Addison Reed | 6.3 | 1.42 | 0 | 5 | X | 0.37 |
| Shane Lindsay | 6.0 | 12.00 | 0 | 4 | X | -1.13 |
| Hector Santiago | 5.3 | 0.00 | 0 | 2 | X | 0.48 |
| Lucas Harrell | 5.0 | 7.20 | 0 | 3 | X | -0.39 |
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