| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 680 | 96 | 83 | 0.298 | 0.379 | 3.70 | 2B |
| Jacoby Ellsbury | 676 | 110 | 96 | 0.316 | 0.373 | 6.62 | CF |
| Adrian Gonzalez | 667 | 105 | 112 | 0.336 | 0.405 | 7.98 | 1B |
| David Ortiz | 554 | 82 | 94 | 0.315 | 0.403 | 6.18 | DH |
| Kevin Youkilis | 517 | 68 | 81 | 0.258 | 0.373 | 4.17 | 3B |
| Carl Crawford | 502 | 62 | 53 | 0.253 | 0.289 | 0.93 | LF |
| Marco Scutaro | 399 | 47 | 49 | 0.288 | 0.341 | 1.22 | SS |
| Jarrod Saltalamacchia | 361 | 51 | 55 | 0.243 | 0.299 | 3.12 | CR |
| Jed Lowrie | 320 | 37 | 31 | 0.252 | 0.300 | 0.04 | SS-3B |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.40 | RF |
| Josh Reddick | 266 | 40 | 29 | 0.289 | 0.338 | 1.34 | RF-LF |
| Jason Varitek | 239 | 32 | 34 | 0.225 | 0.297 | 1.62 | CR |
| Darnell McDonald | 159 | 20 | 21 | 0.211 | 0.283 | 0.78 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Mike Aviles | 75 | 12 | 4 | 0.361 | 0.373 | 0.02 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 32 | 3 | 4 | 0.250 | 0.344 | 0.02 | X |
| Conor Jackson | 9 | 0 | 1 | 0.125 | 0.111 | -0.09 | 1B-RF-LF |
| Jose Iglesias | 5 | 0 | 0 | 0.200 | 0.200 | -0.11 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Lars Anderson | 2 | 0 | 0 | 0.000 | 0.000 | -0.04 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 183.0 | 3.15 | 29 | 0 | X | 3.27 |
| Josh Beckett | 179.7 | 2.50 | 28 | 0 | X | 5.91 |
| John Lackey | 149.7 | 6.19 | 26 | 0 | X | -7.96 |
| Tim Wakefield | 145.7 | 5.13 | 21 | 10 | X | -4.13 |
| Alfredo Aceves | 102.0 | 2.82 | 4 | 45 | X | 2.59 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.83 |
| Daniel Bard | 68.7 | 3.01 | 0 | 66 | X | 1.44 |
| Andrew Miller | 63.0 | 5.43 | 12 | 3 | X | -2.23 |
| Matt Albers | 60.0 | 4.80 | 0 | 52 | X | -1.24 |
| Jonathan Papelbon | 59.7 | 2.56 | 0 | 59 | X | 1.88 |
| Dan Wheeler | 49.3 | 4.56 | 0 | 47 | X | -0.75 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Erik Bedard | 32.0 | 3.66 | 6 | 0 | X | 0.19 |
| Franklin Morales | 29.7 | 3.94 | 0 | 34 | X | -0.02 |
| Scott Atchison | 22.0 | 4.50 | 0 | 12 | X | -0.30 |
| Kyle Weiland | 19.0 | 7.58 | 4 | 1 | X | -1.63 |
| Michael Bowden | 17.0 | 4.76 | 0 | 12 | X | -0.34 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Felix Doubront | 7.3 | 8.59 | 0 | 8 | X | -0.80 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Junichi Tazawa | 1.0 | 9.00 | 0 | 1 | X | -0.12 |
| Trever Miller | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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