| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 668 | 94 | 82 | 0.300 | 0.382 | 3.68 | 2B |
| Jacoby Ellsbury | 664 | 109 | 94 | 0.319 | 0.377 | 6.60 | CF |
| Adrian Gonzalez | 656 | 105 | 111 | 0.340 | 0.407 | 8.14 | 1B |
| David Ortiz | 543 | 82 | 92 | 0.313 | 0.400 | 6.24 | DH |
| Kevin Youkilis | 514 | 68 | 81 | 0.259 | 0.375 | 4.25 | 3B |
| Carl Crawford | 491 | 60 | 53 | 0.250 | 0.285 | 0.98 | LF |
| Marco Scutaro | 388 | 47 | 49 | 0.291 | 0.345 | 1.48 | SS |
| Jarrod Saltalamacchia | 352 | 50 | 55 | 0.249 | 0.304 | 3.22 | CR |
| Jed Lowrie | 320 | 37 | 31 | 0.252 | 0.300 | 0.05 | SS-3B |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.39 | RF |
| Josh Reddick | 256 | 40 | 29 | 0.295 | 0.340 | 1.57 | RF-LF |
| Jason Varitek | 237 | 32 | 34 | 0.226 | 0.295 | 1.68 | CR |
| Darnell McDonald | 158 | 20 | 20 | 0.206 | 0.278 | 0.70 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Mike Aviles | 67 | 10 | 2 | 0.344 | 0.358 | -0.22 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.46 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 31 | 3 | 4 | 0.259 | 0.355 | 0.05 | X |
| Conor Jackson | 6 | 0 | 1 | 0.000 | 0.000 | -0.03 | 1B-RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Lars Anderson | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 176.0 | 3.07 | 28 | 0 | X | 3.48 |
| Josh Beckett | 173.7 | 2.49 | 27 | 0 | X | 5.78 |
| John Lackey | 149.7 | 6.19 | 26 | 0 | X | -7.96 |
| Tim Wakefield | 145.7 | 5.13 | 21 | 10 | X | -4.12 |
| Alfredo Aceves | 101.0 | 2.85 | 4 | 44 | X | 2.51 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.83 |
| Daniel Bard | 66.7 | 3.10 | 0 | 64 | X | 1.26 |
| Andrew Miller | 61.3 | 5.58 | 12 | 2 | X | -2.38 |
| Matt Albers | 59.7 | 4.37 | 0 | 51 | X | -0.64 |
| Jonathan Papelbon | 58.7 | 2.61 | 0 | 58 | X | 1.79 |
| Dan Wheeler | 49.3 | 4.56 | 0 | 47 | X | -0.74 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Erik Bedard | 32.0 | 3.66 | 6 | 0 | X | 0.19 |
| Franklin Morales | 27.7 | 3.58 | 0 | 32 | X | 0.22 |
| Scott Atchison | 21.0 | 4.71 | 0 | 11 | X | -0.39 |
| Kyle Weiland | 16.0 | 6.75 | 3 | 1 | X | -1.06 |
| Michael Bowden | 16.0 | 5.06 | 0 | 11 | X | -0.43 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Felix Doubront | 7.3 | 8.59 | 0 | 8 | X | -0.80 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Junichi Tazawa | 1.0 | 9.00 | 0 | 1 | X | -0.12 |
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