| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 658 | 89 | 77 | 0.296 | 0.380 | 2.81 | 2B |
| Jacoby Ellsbury | 654 | 104 | 91 | 0.315 | 0.373 | 5.94 | CF |
| Adrian Gonzalez | 648 | 102 | 109 | 0.339 | 0.406 | 7.75 | 1B |
| David Ortiz | 543 | 82 | 92 | 0.313 | 0.400 | 6.20 | DH |
| Kevin Youkilis | 506 | 67 | 81 | 0.261 | 0.375 | 4.29 | 3B |
| Carl Crawford | 482 | 57 | 53 | 0.250 | 0.284 | 0.84 | LF |
| Marco Scutaro | 379 | 45 | 46 | 0.287 | 0.343 | 1.13 | SS |
| Jarrod Saltalamacchia | 347 | 48 | 51 | 0.247 | 0.303 | 2.68 | CR |
| Jed Lowrie | 316 | 37 | 31 | 0.255 | 0.304 | 0.12 | SS-3B |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.40 | RF |
| Josh Reddick | 250 | 40 | 29 | 0.298 | 0.344 | 1.69 | RF-LF |
| Jason Varitek | 234 | 32 | 33 | 0.230 | 0.299 | 1.62 | CR |
| Darnell McDonald | 155 | 20 | 20 | 0.203 | 0.277 | 0.76 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Mike Aviles | 66 | 9 | 2 | 0.333 | 0.348 | -0.31 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 28 | 3 | 3 | 0.292 | 0.393 | 0.01 | X |
| Conor Jackson | 5 | 0 | 0 | 0.000 | 0.000 | -0.11 | 1B-RF-LF |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 176.0 | 3.07 | 28 | 0 | X | 3.52 |
| Josh Beckett | 173.7 | 2.49 | 27 | 0 | X | 5.83 |
| John Lackey | 144.3 | 6.30 | 25 | 0 | X | -7.99 |
| Tim Wakefield | 139.7 | 5.03 | 20 | 10 | X | -3.59 |
| Alfredo Aceves | 98.0 | 2.94 | 4 | 42 | X | 2.26 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.85 |
| Daniel Bard | 65.7 | 2.88 | 0 | 63 | X | 1.60 |
| Andrew Miller | 61.3 | 5.58 | 12 | 2 | X | -2.36 |
| Matt Albers | 59.7 | 4.37 | 0 | 51 | X | -0.62 |
| Jonathan Papelbon | 57.7 | 2.65 | 0 | 57 | X | 1.71 |
| Dan Wheeler | 49.3 | 4.56 | 0 | 47 | X | -0.73 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.20 |
| Erik Bedard | 32.0 | 3.66 | 6 | 0 | X | 0.20 |
| Franklin Morales | 27.0 | 3.67 | 0 | 31 | X | 0.16 |
| Scott Atchison | 21.0 | 4.71 | 0 | 11 | X | -0.39 |
| Michael Bowden | 16.0 | 5.06 | 0 | 11 | X | -0.42 |
| Kyle Weiland | 16.0 | 6.75 | 3 | 1 | X | -1.05 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.87 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Felix Doubront | 7.3 | 8.59 | 0 | 8 | X | -0.80 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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