| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 641 | 88 | 77 | 0.301 | 0.385 | 3.11 | 2B |
| Adrian Gonzalez | 636 | 101 | 107 | 0.343 | 0.407 | 7.74 | 1B |
| Jacoby Ellsbury | 635 | 102 | 88 | 0.315 | 0.373 | 5.87 | CF |
| David Ortiz | 526 | 81 | 92 | 0.319 | 0.407 | 6.50 | DH |
| Kevin Youkilis | 502 | 67 | 81 | 0.263 | 0.376 | 4.41 | 3B |
| Carl Crawford | 471 | 57 | 53 | 0.249 | 0.285 | 1.11 | LF |
| Marco Scutaro | 361 | 44 | 42 | 0.285 | 0.343 | 1.03 | SS |
| Jarrod Saltalamacchia | 339 | 46 | 50 | 0.247 | 0.304 | 2.56 | CR |
| Jed Lowrie | 304 | 37 | 30 | 0.266 | 0.316 | 0.29 | SS-3B |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.39 | RF |
| Josh Reddick | 236 | 39 | 29 | 0.294 | 0.343 | 1.91 | RF-LF |
| Jason Varitek | 227 | 30 | 32 | 0.232 | 0.300 | 1.48 | CR |
| Darnell McDonald | 149 | 19 | 20 | 0.201 | 0.268 | 0.79 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Mike Aviles | 63 | 9 | 2 | 0.317 | 0.333 | -0.24 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 27 | 3 | 3 | 0.304 | 0.407 | 0.03 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Conor Jackson | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | 1B-RF-LF |
| Nate Spears | 2 | 0 | 0 | 0.000 | 0.000 | -0.04 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 173.7 | 2.49 | 27 | 0 | X | 5.78 |
| Jon Lester | 172.0 | 2.93 | 27 | 0 | X | 3.94 |
| John Lackey | 141.3 | 6.11 | 24 | 0 | X | -7.26 |
| Tim Wakefield | 139.7 | 5.03 | 20 | 10 | X | -3.63 |
| Alfredo Aceves | 94.0 | 2.87 | 4 | 41 | X | 2.28 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.83 |
| Daniel Bard | 65.3 | 2.76 | 0 | 62 | X | 1.76 |
| Matt Albers | 57.7 | 4.37 | 0 | 49 | X | -0.62 |
| Andrew Miller | 56.3 | 5.27 | 11 | 2 | X | -1.79 |
| Jonathan Papelbon | 55.7 | 2.75 | 0 | 56 | X | 1.51 |
| Dan Wheeler | 49.3 | 4.56 | 0 | 47 | X | -0.75 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Erik Bedard | 32.0 | 3.66 | 6 | 0 | X | 0.19 |
| Franklin Morales | 25.0 | 3.96 | 0 | 29 | X | -0.03 |
| Scott Atchison | 18.3 | 4.42 | 0 | 10 | X | -0.22 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Michael Bowden | 13.7 | 3.29 | 0 | 9 | X | 0.20 |
| Kyle Weiland | 12.0 | 6.75 | 2 | 1 | X | -0.79 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Felix Doubront | 4.3 | 10.38 | 0 | 5 | X | -0.65 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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