| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 626 | 87 | 77 | 0.307 | 0.393 | 3.28 | 2B |
| Adrian Gonzalez | 621 | 96 | 104 | 0.340 | 0.404 | 7.18 | 1B |
| Jacoby Ellsbury | 620 | 98 | 85 | 0.310 | 0.369 | 5.41 | CF |
| David Ortiz | 510 | 76 | 89 | 0.314 | 0.402 | 5.97 | DH |
| Kevin Youkilis | 486 | 65 | 79 | 0.263 | 0.374 | 4.30 | 3B |
| Carl Crawford | 457 | 56 | 52 | 0.252 | 0.284 | 1.17 | LF |
| Marco Scutaro | 346 | 41 | 35 | 0.271 | 0.329 | 0.28 | SS |
| Jarrod Saltalamacchia | 330 | 45 | 48 | 0.251 | 0.309 | 2.42 | CR |
| Jed Lowrie | 303 | 37 | 30 | 0.266 | 0.314 | 0.29 | SS-3B |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.41 | RF |
| Josh Reddick | 226 | 37 | 27 | 0.289 | 0.341 | 1.69 | RF-LF |
| Jason Varitek | 223 | 30 | 32 | 0.236 | 0.305 | 1.55 | CR |
| Darnell McDonald | 144 | 19 | 19 | 0.194 | 0.264 | 0.78 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.45 | CF |
| Mike Aviles | 62 | 9 | 2 | 0.322 | 0.339 | -0.23 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.05 | X |
| Ryan Lavarnway | 27 | 3 | 3 | 0.304 | 0.407 | 0.03 | X |
| Conor Jackson | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | 1B-RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 170.0 | 2.54 | 26 | 0 | X | 5.45 |
| Jon Lester | 165.0 | 3.05 | 26 | 0 | X | 3.32 |
| John Lackey | 141.3 | 6.11 | 24 | 0 | X | -7.24 |
| Tim Wakefield | 134.7 | 4.95 | 19 | 10 | X | -3.23 |
| Alfredo Aceves | 90.3 | 2.99 | 4 | 40 | X | 1.95 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.83 |
| Daniel Bard | 62.7 | 2.15 | 0 | 60 | X | 2.58 |
| Matt Albers | 57.3 | 4.40 | 0 | 48 | X | -0.64 |
| Andrew Miller | 56.3 | 5.27 | 11 | 2 | X | -1.78 |
| Jonathan Papelbon | 54.7 | 2.80 | 0 | 55 | X | 1.43 |
| Dan Wheeler | 47.3 | 4.37 | 0 | 45 | X | -0.50 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Erik Bedard | 32.0 | 3.66 | 6 | 0 | X | 0.19 |
| Franklin Morales | 24.7 | 4.01 | 0 | 28 | X | -0.06 |
| Scott Atchison | 18.3 | 4.42 | 0 | 10 | X | -0.21 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Michael Bowden | 13.7 | 3.29 | 0 | 9 | X | 0.20 |
| Kyle Weiland | 10.0 | 8.10 | 2 | 0 | X | -0.98 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Felix Doubront | 4.3 | 10.38 | 0 | 5 | X | -0.65 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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