| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 623 | 87 | 77 | 0.309 | 0.395 | 3.37 | 2B |
| Adrian Gonzalez | 617 | 95 | 104 | 0.342 | 0.405 | 7.18 | 1B |
| Jacoby Ellsbury | 615 | 98 | 85 | 0.311 | 0.371 | 5.54 | CF |
| David Ortiz | 506 | 76 | 88 | 0.311 | 0.399 | 5.97 | DH |
| Kevin Youkilis | 482 | 64 | 79 | 0.261 | 0.373 | 4.30 | 3B |
| Carl Crawford | 453 | 55 | 52 | 0.252 | 0.285 | 1.16 | LF |
| Marco Scutaro | 342 | 41 | 33 | 0.270 | 0.327 | 0.17 | SS |
| Jarrod Saltalamacchia | 326 | 44 | 48 | 0.251 | 0.310 | 2.41 | CR |
| Jed Lowrie | 303 | 37 | 30 | 0.266 | 0.314 | 0.30 | SS-3B |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.41 | RF |
| Josh Reddick | 226 | 37 | 27 | 0.289 | 0.341 | 1.70 | RF-LF |
| Jason Varitek | 223 | 30 | 32 | 0.236 | 0.305 | 1.55 | CR |
| Darnell McDonald | 141 | 19 | 18 | 0.189 | 0.262 | 0.75 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.44 | CF |
| Mike Aviles | 60 | 9 | 2 | 0.333 | 0.350 | -0.18 | 3B-2B |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.45 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 27 | 3 | 3 | 0.304 | 0.407 | 0.03 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Conor Jackson | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | 1B-RF-LF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 170.0 | 2.54 | 26 | 0 | X | 5.44 |
| Jon Lester | 165.0 | 3.05 | 26 | 0 | X | 3.31 |
| John Lackey | 136.3 | 5.94 | 23 | 0 | X | -6.45 |
| Tim Wakefield | 134.7 | 4.95 | 19 | 10 | X | -3.24 |
| Alfredo Aceves | 90.3 | 2.99 | 4 | 40 | X | 1.95 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.83 |
| Daniel Bard | 62.7 | 2.15 | 0 | 60 | X | 2.57 |
| Andrew Miller | 56.3 | 5.27 | 11 | 2 | X | -1.79 |
| Matt Albers | 55.7 | 4.53 | 0 | 47 | X | -0.80 |
| Jonathan Papelbon | 54.7 | 2.80 | 0 | 55 | X | 1.42 |
| Dan Wheeler | 47.3 | 4.37 | 0 | 45 | X | -0.51 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.21 |
| Erik Bedard | 32.0 | 3.66 | 6 | 0 | X | 0.19 |
| Franklin Morales | 24.7 | 4.01 | 0 | 28 | X | -0.06 |
| Scott Atchison | 18.3 | 4.42 | 0 | 10 | X | -0.22 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.88 |
| Michael Bowden | 11.7 | 2.31 | 0 | 8 | X | 0.44 |
| Kyle Weiland | 10.0 | 8.10 | 2 | 0 | X | -0.98 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.26 |
| Felix Doubront | 4.0 | 4.50 | 0 | 4 | X | -0.05 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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