| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 562 | 62 | 39 | 0.284 | 0.326 | -2.29 | LF |
| Alexei Ramirez | 538 | 69 | 54 | 0.261 | 0.323 | 0.57 | SS |
| Paul Konerko | 520 | 62 | 86 | 0.314 | 0.398 | 3.61 | 1B-DH |
| Carlos Quentin | 481 | 60 | 76 | 0.255 | 0.341 | 3.25 | RF-DH |
| Alex Rios | 464 | 48 | 31 | 0.212 | 0.252 | -2.35 | CF |
| Gordon Beckham | 436 | 46 | 34 | 0.235 | 0.289 | -1.60 | 2B |
| Adam Dunn | 431 | 33 | 40 | 0.165 | 0.292 | -2.22 | DH-1B |
| A.J. Pierzynski | 402 | 32 | 39 | 0.296 | 0.336 | -1.77 | CR |
| Brent Morel | 320 | 30 | 22 | 0.256 | 0.275 | -1.88 | 3B |
| Brent Lillibridge | 187 | 23 | 24 | 0.263 | 0.337 | 0.65 | RF-1B-CF |
| Omar Vizquel | 169 | 14 | 8 | 0.248 | 0.278 | -1.57 | 3B-2B |
| Mark Teahen | 130 | 10 | 11 | 0.203 | 0.277 | -0.78 | X |
| Ramon Castro | 75 | 6 | 10 | 0.235 | 0.307 | -0.04 | CR |
| Alejandro de Aza | 64 | 8 | 9 | 0.317 | 0.359 | 0.32 | RF-CF |
| Tyler Flowers | 53 | 6 | 3 | 0.289 | 0.396 | -0.27 | CR |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | -0.24 | X |
| Donny Lucy | 4 | 0 | 0 | 0.250 | 0.250 | -0.09 | X |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 169.3 | 3.14 | 25 | 0 | X | 2.87 |
| Gavin Floyd | 155.7 | 4.45 | 24 | 1 | X | -2.14 |
| John Danks | 132.3 | 3.88 | 21 | 0 | X | -0.04 |
| Philip Humber | 131.3 | 3.63 | 21 | 2 | X | 0.71 |
| Edwin Jackson | 121.7 | 3.92 | 19 | 0 | X | -0.16 |
| Jake Peavy | 94.3 | 5.06 | 15 | 1 | X | -2.63 |
| Chris Sale | 57.7 | 2.65 | 0 | 47 | X | 1.63 |
| Jesse Crain | 57.3 | 2.51 | 0 | 55 | X | 1.81 |
| Sergio Santos | 52.7 | 2.73 | 0 | 51 | X | 1.39 |
| Matt Thornton | 45.3 | 3.38 | 0 | 48 | X | 0.52 |
| Will Ohman | 41.7 | 4.10 | 0 | 44 | X | -0.23 |
| Zach Stewart | 23.0 | 4.70 | 3 | 2 | X | -0.45 |
| Tony Pena | 20.3 | 6.20 | 0 | 17 | X | -1.11 |
| Brian Bruney | 19.7 | 6.86 | 0 | 23 | X | -1.38 |
| Jeff Gray | 13.3 | 2.70 | 0 | 6 | X | 0.36 |
| Jason Frasor | 9.0 | 6.00 | 0 | 12 | X | -0.45 |
| Hector Santiago | 5.3 | 0.00 | 0 | 2 | X | 0.48 |
| Lucas Harrell | 5.0 | 7.20 | 0 | 3 | X | -0.39 |
| Josh Kinney | 5.0 | 1.80 | 0 | 2 | X | 0.24 |
_