| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 581 | 80 | 67 | 0.305 | 0.394 | 2.58 | 2B |
| Adrian Gonzalez | 574 | 86 | 98 | 0.346 | 0.408 | 6.62 | 1B |
| Jacoby Ellsbury | 567 | 90 | 79 | 0.311 | 0.367 | 5.20 | CF |
| Kevin Youkilis | 474 | 64 | 79 | 0.266 | 0.380 | 4.52 | 3B |
| David Ortiz | 464 | 67 | 79 | 0.300 | 0.388 | 5.06 | DH |
| Carl Crawford | 419 | 50 | 41 | 0.251 | 0.286 | 0.28 | LF |
| Marco Scutaro | 305 | 37 | 29 | 0.272 | 0.334 | 0.18 | SS |
| Jarrod Saltalamacchia | 300 | 41 | 42 | 0.247 | 0.307 | 2.07 | CR |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.38 | RF |
| Jed Lowrie | 267 | 34 | 28 | 0.267 | 0.311 | 0.60 | SS-3B |
| Jason Varitek | 208 | 27 | 26 | 0.228 | 0.303 | 0.96 | CR |
| Josh Reddick | 198 | 31 | 26 | 0.291 | 0.338 | 1.60 | RF-LF |
| Darnell McDonald | 125 | 17 | 18 | 0.188 | 0.264 | 0.91 | RF-LF-CF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.43 | CF |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.46 | X |
| Mike Aviles | 46 | 6 | 1 | 0.295 | 0.304 | -0.28 | 3B-2B |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.06 | X |
| Ryan Lavarnway | 26 | 3 | 3 | 0.318 | 0.423 | 0.05 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 157.0 | 2.46 | 24 | 0 | X | 5.24 |
| Jon Lester | 154.0 | 3.16 | 24 | 0 | X | 2.66 |
| John Lackey | 129.3 | 5.98 | 22 | 0 | X | -6.31 |
| Tim Wakefield | 126.7 | 4.97 | 18 | 9 | X | -3.19 |
| Alfredo Aceves | 83.3 | 3.02 | 4 | 36 | X | 1.69 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.79 |
| Daniel Bard | 60.0 | 2.10 | 0 | 57 | X | 2.51 |
| Matt Albers | 52.0 | 3.46 | 0 | 43 | X | 0.53 |
| Jonathan Papelbon | 51.7 | 2.96 | 0 | 52 | X | 1.13 |
| Andrew Miller | 48.7 | 4.99 | 9 | 2 | X | -1.25 |
| Dan Wheeler | 43.0 | 4.19 | 0 | 41 | X | -0.29 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.23 |
| Franklin Morales | 22.0 | 4.09 | 0 | 25 | X | -0.10 |
| Erik Bedard | 22.0 | 4.09 | 4 | 0 | X | -0.10 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.89 |
| Scott Atchison | 15.3 | 4.70 | 0 | 9 | X | -0.29 |
| Kyle Weiland | 10.0 | 8.10 | 2 | 0 | X | -0.98 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Randy Williams | 8.3 | 6.48 | 0 | 7 | X | -0.50 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.43 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
_