| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 481 | 52 | 27 | 0.277 | 0.324 | -2.75 | LF |
| Alexei Ramirez | 463 | 60 | 46 | 0.267 | 0.324 | 0.50 | SS |
| Paul Konerko | 443 | 53 | 76 | 0.308 | 0.388 | 3.37 | 1B-DH |
| Carlos Quentin | 431 | 54 | 69 | 0.259 | 0.346 | 3.02 | RF-DH |
| Alex Rios | 401 | 42 | 24 | 0.207 | 0.252 | -2.28 | CF |
| Adam Dunn | 391 | 31 | 39 | 0.165 | 0.297 | -1.63 | DH-1B |
| A.J. Pierzynski | 378 | 31 | 34 | 0.283 | 0.323 | -1.86 | CR |
| Gordon Beckham | 373 | 39 | 31 | 0.247 | 0.300 | -1.22 | 2B |
| Brent Morel | 256 | 20 | 18 | 0.258 | 0.273 | -1.89 | 3B |
| Omar Vizquel | 153 | 12 | 8 | 0.252 | 0.275 | -1.41 | 3B-2B |
| Brent Lillibridge | 153 | 17 | 15 | 0.252 | 0.327 | -0.15 | RF-1B-CF |
| Mark Teahen | 130 | 10 | 11 | 0.203 | 0.277 | -0.78 | X |
| Ramon Castro | 75 | 6 | 10 | 0.235 | 0.307 | -0.04 | CR |
| Alejandro de Aza | 22 | 3 | 2 | 0.318 | 0.318 | 0.02 | RF-CF |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | -0.24 | X |
| Tyler Flowers | 9 | 1 | 0 | 0.125 | 0.222 | -0.10 | CR |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 148.0 | 2.98 | 22 | 0 | X | 3.00 |
| Gavin Floyd | 136.3 | 4.56 | 21 | 1 | X | -2.25 |
| Philip Humber | 124.0 | 3.56 | 19 | 2 | X | 0.85 |
| Edwin Jackson | 121.7 | 3.92 | 19 | 0 | X | -0.20 |
| John Danks | 113.0 | 3.90 | 18 | 0 | X | -0.14 |
| Jake Peavy | 73.7 | 5.13 | 12 | 1 | X | -2.20 |
| Chris Sale | 51.0 | 2.82 | 0 | 42 | X | 1.22 |
| Jesse Crain | 48.3 | 2.79 | 0 | 49 | X | 1.19 |
| Sergio Santos | 46.3 | 2.91 | 0 | 44 | X | 1.01 |
| Matt Thornton | 37.7 | 3.58 | 0 | 42 | X | 0.23 |
| Will Ohman | 37.3 | 4.10 | 0 | 37 | X | -0.22 |
| Tony Pena | 20.3 | 6.20 | 0 | 17 | X | -1.11 |
| Brian Bruney | 19.7 | 6.86 | 0 | 23 | X | -1.38 |
| Jeff Gray | 13.3 | 2.70 | 0 | 6 | X | 0.36 |
| Hector Santiago | 5.3 | 0.00 | 0 | 2 | X | 0.48 |
| Lucas Harrell | 5.0 | 7.20 | 0 | 3 | X | -0.39 |
| Jason Frasor | 2.3 | 11.57 | 0 | 3 | X | -0.42 |
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