| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 494 | 74 | 57 | 0.310 | 0.405 | 3.03 | 2B |
| Jacoby Ellsbury | 485 | 81 | 63 | 0.317 | 0.373 | 4.59 | CF |
| Adrian Gonzalez | 483 | 76 | 91 | 0.356 | 0.416 | 7.05 | 1B |
| Kevin Youkilis | 429 | 59 | 76 | 0.275 | 0.389 | 4.86 | 3B |
| David Ortiz | 413 | 58 | 68 | 0.290 | 0.375 | 4.26 | DH |
| Carl Crawford | 334 | 42 | 37 | 0.247 | 0.281 | 1.04 | LF |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.27 | RF |
| Marco Scutaro | 255 | 31 | 21 | 0.272 | 0.341 | -0.08 | SS |
| Jarrod Saltalamacchia | 249 | 34 | 36 | 0.265 | 0.329 | 1.94 | CR |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.77 | SS-3B |
| Jason Varitek | 177 | 24 | 22 | 0.237 | 0.311 | 0.99 | CR |
| Josh Reddick | 137 | 24 | 22 | 0.328 | 0.372 | 1.85 | RF-LF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.39 | CF |
| Darnell McDonald | 93 | 13 | 13 | 0.171 | 0.269 | 0.71 | RF-LF-CF |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.48 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.08 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Mike Aviles | 3 | 1 | 0 | 0.333 | 0.333 | 0.04 | 3B-2B |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 133.0 | 2.17 | 20 | 0 | X | 5.20 |
| Jon Lester | 127.7 | 3.17 | 20 | 0 | X | 1.99 |
| John Lackey | 104.0 | 6.23 | 18 | 0 | X | -5.80 |
| Tim Wakefield | 99.7 | 5.06 | 14 | 9 | X | -2.83 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.69 |
| Alfredo Aceves | 73.3 | 3.19 | 4 | 27 | X | 1.11 |
| Daniel Bard | 51.3 | 2.28 | 0 | 50 | X | 1.87 |
| Matt Albers | 44.0 | 2.25 | 0 | 36 | X | 1.63 |
| Jonathan Papelbon | 43.7 | 3.50 | 0 | 44 | X | 0.34 |
| Andrew Miller | 40.3 | 5.36 | 8 | 0 | X | -1.42 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.27 |
| Dan Wheeler | 35.7 | 4.79 | 0 | 33 | X | -0.79 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.91 |
| Scott Atchison | 15.3 | 4.70 | 0 | 9 | X | -0.31 |
| Franklin Morales | 14.0 | 4.50 | 0 | 15 | X | -0.22 |
| Kyle Weiland | 10.0 | 8.10 | 2 | 0 | X | -0.99 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Randy Williams | 6.3 | 8.53 | 0 | 5 | X | -0.69 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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