| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 489 | 74 | 57 | 0.309 | 0.405 | 3.14 | 2B |
| Jacoby Ellsbury | 480 | 81 | 62 | 0.319 | 0.375 | 4.60 | CF |
| Adrian Gonzalez | 479 | 75 | 91 | 0.357 | 0.418 | 7.03 | 1B |
| Kevin Youkilis | 425 | 59 | 75 | 0.273 | 0.388 | 4.84 | 3B |
| David Ortiz | 409 | 58 | 68 | 0.293 | 0.379 | 4.35 | DH |
| Carl Crawford | 330 | 40 | 36 | 0.244 | 0.279 | 0.82 | LF |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.26 | RF |
| Marco Scutaro | 254 | 31 | 20 | 0.269 | 0.339 | -0.16 | SS |
| Jarrod Saltalamacchia | 245 | 32 | 34 | 0.261 | 0.327 | 1.61 | CR |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.77 | SS-3B |
| Jason Varitek | 177 | 24 | 22 | 0.237 | 0.311 | 0.99 | CR |
| Josh Reddick | 133 | 24 | 22 | 0.331 | 0.376 | 1.94 | RF-LF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.39 | CF |
| Darnell McDonald | 93 | 13 | 13 | 0.171 | 0.269 | 0.71 | RF-LF-CF |
| Drew Sutton | 60 | 10 | 7 | 0.309 | 0.350 | 0.48 | X |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.08 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 133.0 | 2.17 | 20 | 0 | X | 5.19 |
| Jon Lester | 127.7 | 3.17 | 20 | 0 | X | 1.98 |
| Tim Wakefield | 99.7 | 5.06 | 14 | 9 | X | -2.83 |
| John Lackey | 97.3 | 6.20 | 17 | 0 | X | -5.35 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.68 |
| Alfredo Aceves | 73.3 | 3.19 | 4 | 27 | X | 1.11 |
| Daniel Bard | 51.0 | 1.76 | 0 | 49 | X | 2.47 |
| Jonathan Papelbon | 43.7 | 3.50 | 0 | 44 | X | 0.34 |
| Matt Albers | 43.0 | 2.09 | 0 | 35 | X | 1.75 |
| Andrew Miller | 40.3 | 5.36 | 8 | 0 | X | -1.43 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.28 |
| Dan Wheeler | 35.7 | 4.79 | 0 | 33 | X | -0.80 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.91 |
| Scott Atchison | 15.3 | 4.70 | 0 | 9 | X | -0.31 |
| Franklin Morales | 13.7 | 4.61 | 0 | 14 | X | -0.25 |
| Kyle Weiland | 10.0 | 8.10 | 2 | 0 | X | -0.99 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Randy Williams | 5.7 | 9.53 | 0 | 4 | X | -0.75 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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