| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 466 | 70 | 51 | 0.304 | 0.403 | 2.63 | 2B |
| Adrian Gonzalez | 460 | 73 | 85 | 0.348 | 0.411 | 6.64 | 1B |
| Jacoby Ellsbury | 456 | 75 | 58 | 0.319 | 0.375 | 4.10 | CF |
| Kevin Youkilis | 403 | 57 | 73 | 0.279 | 0.395 | 4.93 | 3B |
| David Ortiz | 387 | 57 | 64 | 0.306 | 0.393 | 4.34 | DH |
| Carl Crawford | 316 | 38 | 36 | 0.247 | 0.282 | 0.94 | LF |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.24 | RF |
| Marco Scutaro | 238 | 29 | 17 | 0.262 | 0.332 | -0.32 | SS |
| Jarrod Saltalamacchia | 233 | 29 | 31 | 0.256 | 0.322 | 1.26 | CR |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.79 | SS-3B |
| Jason Varitek | 170 | 22 | 20 | 0.235 | 0.312 | 0.73 | CR |
| Josh Reddick | 119 | 22 | 22 | 0.362 | 0.403 | 2.05 | RF-LF |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.38 | CF |
| Darnell McDonald | 86 | 10 | 13 | 0.156 | 0.244 | 0.56 | RF-LF-CF |
| Drew Sutton | 54 | 10 | 7 | 0.286 | 0.333 | 0.62 | X |
| Yamaico Navarro | 31 | 4 | 2 | 0.179 | 0.258 | -0.04 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 126.0 | 2.07 | 19 | 0 | X | 5.17 |
| Jon Lester | 119.7 | 3.23 | 19 | 0 | X | 1.67 |
| Tim Wakefield | 92.7 | 5.15 | 13 | 9 | X | -2.85 |
| John Lackey | 91.7 | 6.28 | 16 | 0 | X | -5.25 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.67 |
| Alfredo Aceves | 71.3 | 3.28 | 4 | 25 | X | 0.92 |
| Daniel Bard | 49.7 | 1.81 | 0 | 48 | X | 2.34 |
| Jonathan Papelbon | 42.7 | 3.59 | 0 | 43 | X | 0.24 |
| Matt Albers | 42.0 | 2.14 | 0 | 34 | X | 1.65 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.28 |
| Andrew Miller | 34.7 | 5.45 | 7 | 0 | X | -1.31 |
| Dan Wheeler | 33.0 | 5.18 | 0 | 31 | X | -1.04 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.91 |
| Scott Atchison | 15.3 | 4.70 | 0 | 9 | X | -0.31 |
| Franklin Morales | 12.7 | 4.97 | 0 | 13 | X | -0.34 |
| Kyle Weiland | 10.0 | 8.10 | 2 | 0 | X | -1.00 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.10 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Randy Williams | 4.0 | 11.25 | 0 | 3 | X | -0.69 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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